Cheruvu Vinay K, Bhatta Madhav P, Drinkard Lauren N
Department of Biostatistics, Environmental Health Sciences, and Epidemiology, College of Public Health, Kent State University, Hilltop Drive, 320 Lowry Hall, Kent, 44242, OH, USA.
BMC Pediatr. 2017 Feb 13;17(1):52. doi: 10.1186/s12887-017-0804-1.
Data from 2008-2012 National Immunization Survey - Teen (NIS - Teen) were examined in this study. Parents with "no-intent" to vaccinate their daughters were asked to identify reasons for their decision. All responses were categorized into five domains identified as barriers to receive the HPV vaccine series: 1) Safety and Effectiveness Concerns; 2) Systemic Barriers; 3) Vaccine Misinformation; 4) Lack of Knowledge about the Vaccine; and 5) Socio-cultural Barriers. Multivariable logistic regression models were performed to address the study objectives.
Number of people in the household, household income, mother's age, education, health insurance, recommendation of a health care provider, and the survey year were significantly associated with parental "no-intent". Race/ethnicity, mother's education, marital status, recommendation of a health care provider, household income, age of the unvaccinated daughter, and the survey year, were significantly associated with one or more domains identified as barriers to receive the HPV vaccine.
This study identified sub-groups of parents across different socio-demographic factors with "no-intent" for their adolescent daughters to receive the HPV vaccine. Developing strategies that target educational tools towards the identified sub-groups of parents about the purpose, safety, and efficacy of the HPV vaccine, and HPV infection, may help increase HPV vaccine acceptance, initiation and completion rates.
1)确定与父母“无意”让其13至17岁未接种疫苗的女儿在未来十二个月内接种人乳头瘤病毒(HPV)疫苗系列相关的社会人口学因素;2)按社会人口学因素描述“无意”模式;3)确定与父母“无意”原因相关的社会人口学因素。
本研究分析了2008 - 2012年全国青少年免疫调查(NIS - Teen)的数据。询问了那些“无意”为女儿接种疫苗的父母做出该决定的原因。所有回答被归为五个领域,这些领域被确定为接种HPV疫苗系列的障碍:1)对安全性和有效性的担忧;2)系统性障碍;3)疫苗错误信息;4)对疫苗缺乏了解;5)社会文化障碍。采用多变量逻辑回归模型来实现研究目标。
家庭人口数量、家庭收入、母亲年龄、教育程度、医疗保险、医疗保健提供者的建议以及调查年份与父母的“无意”显著相关。种族/族裔、母亲的教育程度、婚姻状况、医疗保健提供者的建议、家庭收入、未接种疫苗女儿的年龄以及调查年份与被确定为接种HPV疫苗障碍的一个或多个领域显著相关。
本研究确定了不同社会人口学因素下“无意”让其青春期女儿接种HPV疫苗的父母亚组。针对已确定的父母亚组制定有关HPV疫苗的目的、安全性和有效性以及HPV感染的教育工具策略,可能有助于提高HPV疫苗的接受率、起始接种率和全程接种率。