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多发性硬化症患者用芬戈莫德治疗后生育的婴儿出现神经发育迟缓。

Neurodevelopmental retardation in a baby born to a multiple sclerosis patient being treated with fingolimod.

机构信息

Assistant Professor of Neurology, Neurology Department, Booalisina Hospital, Mazandaran University of Medical Sciences, Pasdaran Boulevard, Sari, Iran.

Assistant Professor of Pediatric Neurology, Pediatric Neurology Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran Iran.

出版信息

Mult Scler Relat Disord. 2019 Aug;33:116-120. doi: 10.1016/j.msard.2019.05.016. Epub 2019 May 30.

DOI:10.1016/j.msard.2019.05.016
PMID:31185372
Abstract

This report is about a female child born to a multiple sclerosis mother who continued fingolimod during her first trimester of pregnancy. The child was born with normal full-term delivery but showed neurodevelopmental retardation in the following years. it is recommended that multiple sclerosis patients undergoing treatment with fingolimod use contraceptive methods for at least two months after discontinuation of the medication.

摘要

本报告涉及一位多发性硬化症母亲在怀孕首三个月继续服用芬戈莫德的情况下所生的女婴。该婴儿足月正常分娩,但在随后的几年中表现出神经发育迟缓。建议接受芬戈莫德治疗的多发性硬化症患者在停药至少两个月后使用避孕方法。

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