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尾骶部阻滞联合镇痛镇静——小儿下腹部手术的一种更优麻醉技术。

Caudal block with analgosedation - a superior anaesthesia technique for lower abdominal surgery in paediatric population.

作者信息

Šabanović Adilović Adisa, Rizvanović Nermina, Adilović Harun, Ejubović Malik, Jakić Azur, Maksić Hajrija, Simić Dušica

机构信息

Department of Anaesthesiology and Intensive Care Unit, Cantonal Hospital Zenica, Bosnia and Herzegovina.

Department of Internal Medicine, Cantonal Hospital Zenica, Bosnia and Herzegovina.

出版信息

Med Glas (Zenica). 2019 Aug 1;16(2). doi: 10.17392/1017-19.

Abstract

Aim To compare intraoperative hemodynamic and respiratory stability and postoperative emergence delirium between two anaesthesia regimens in children (caudal block with intravenous continuous analgosedation versus general endotracheal anaesthesia) and intensity of postoperative pain and quality of postoperative analgesia. Method Forty children aged 2-6 years who underwent lower abdominal surgery were randomized depending on performed anaesthesia into two groups: caudal block with analgosedation (group CB) and general endotracheal anaesthesia (group GA). Intraoperative hemodynamic and respiratory stability were evaluated measuring systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), heart rate (HR) and arterial oxygen saturation (SaO2) in preinduction (t0), at the moment of surgical incision (t1), 10 minutes after surgical incision (t2) and at the time of skin suturing (t3). Postoperative emergence delirium was evaluated using Paediatric Anaesthesia Emergence Delirium score (PAED). Postoperative pain was evaluated by Children's and Infants' Postoperative Pain score (CHIPPS). Both scores were recorded every 5 minutes during first half hour postoperatively, additionally after 60 minutes postoperatively for CHIPPS score. Results SBP, DBP and MAP were lower at t1 (p<0.0001), t2 (p<0.05) and t3 (p<0.001) in the group CB. HR was lower at all studied time points (p<0.005) in the group CB. SaO2 was lower in the CB group but comparable with the GA group. PAED and CHIPPS scores were lower at 5, 10, 15, 20 and 25 minutes postoperatively (p<0.001) in the CB group. Conclusion Caudal block with analgosedation provides better control of intraoperative hemodynamic conditions, postoperative emergence delirium and postoperative pain than general endotracheal anaesthesia.

摘要

目的 比较两种麻醉方案(骶管阻滞联合静脉持续镇痛镇静与全身气管内麻醉)用于儿童时的术中血流动力学和呼吸稳定性、术后谵妄以及术后疼痛强度和镇痛质量。方法 将40例2至6岁接受下腹部手术的儿童根据所实施的麻醉随机分为两组:骶管阻滞联合镇痛镇静组(CB组)和全身气管内麻醉组(GA组)。通过测量诱导前(t0)、手术切口时(t1)、手术切口后10分钟(t2)和皮肤缝合时(t3)的收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、心率(HR)和动脉血氧饱和度(SaO2)来评估术中血流动力学和呼吸稳定性。使用小儿麻醉苏醒期谵妄评分(PAED)评估术后谵妄。通过儿童和婴儿术后疼痛评分(CHIPPS)评估术后疼痛。术后半小时内每5分钟记录一次这两个评分,术后60分钟时额外记录CHIPPS评分。结果 CB组在t1(p<0.0001)、t2(p<0.05)和t3(p<0.001)时SBP、DBP和MAP较低。CB组在所有研究时间点HR均较低(p<0.005)。CB组的SaO2较低,但与GA组相当。CB组术后5、10、15、20和25分钟时PAED和CHIPPS评分较低(p<0.001)。结论 骶管阻滞联合镇痛镇静比全身气管内麻醉能更好地控制术中血流动力学状况、术后谵妄和术后疼痛。

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