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偏远地区的老年原住民潜在的药物处方不理想。

Potentially suboptimal prescribing of medicines for older Aboriginal Australians in remote areas.

机构信息

Western Australian Centre for Health and Ageing, University of Western Australia, Perth, WA.

Alfred Health, Melbourne, VIC.

出版信息

Med J Aust. 2019 Aug;211(3):119-125. doi: 10.5694/mja2.50226. Epub 2019 Jun 12.

Abstract

OBJECTIVES

To investigate the prevalence of polypharmacy, under-prescribing and potentially inappropriate medicine use among Aboriginal Australians living in remote Western Australia.

DESIGN

Cross-sectional study.

SETTING

Six remote communities and the town of Derby in the Kimberley, Western Australia.

PARTICIPANTS

Aboriginal people aged 45 years or more with complete medication histories.

MAIN OUTCOME MEASURES

Proportions of patients with medicine histories indicating polypharmacy, potential under-prescribing of indicated medicines, or potentially inappropriate prescribing (including potential prescribing cascades or drug interactions).

RESULTS

Complete medicine histories were available for 273 participants. The mean number of prescribed medicines was 5.1 (SD, 3.6). At least one form of suboptimal prescribing was identified for 166 participants (61%), including polypharmacy for 145 (53%), potential under-prescribing of at least one indicated medicine for 33 (12%), and potentially inappropriate prescribing for 54 participants (20%). Potential prescribing cascades or drug interactions were identified for 12 participants (4%).

CONCLUSIONS

Potentially suboptimal prescribing affected more than half the participating older Aboriginal Australians from the Kimberley. If generalisable to other remote Indigenous Australians, the prevalence of polypharmacy, potentially inappropriate prescribing, and under-prescribing of indicated medicines is problematic, and suggests that older Indigenous people in remote areas are at risk of medicine-related harm.

摘要

目的

调查居住在西澳大利亚偏远地区的澳大利亚原住民中,多重用药、用药不足和潜在不适当用药的流行情况。

设计

横断面研究。

地点

西澳大利亚金伯利地区的六个偏远社区和德比镇。

参与者

年龄在 45 岁及以上、有完整用药史的原住民。

主要观察指标

有用药史提示多重用药、潜在指示性药物用药不足或潜在不适当用药(包括潜在用药级联或药物相互作用)的患者比例。

结果

273 名参与者提供了完整的用药史。处方药物的平均数量为 5.1(SD,3.6)。166 名参与者(61%)至少存在一种形式的用药不当,其中 145 名(53%)存在多重用药,33 名(12%)存在至少一种指示性药物潜在用药不足,54 名(20%)存在潜在不适当用药。12 名参与者(4%)存在潜在的用药级联或药物相互作用。

结论

潜在的用药不当影响了金伯利地区超过一半的参与研究的老年原住民。如果可以推广到其他偏远地区的原住民,那么多重用药、潜在不适当用药和指示性药物用药不足的流行率是成问题的,这表明偏远地区的老年原住民面临着药物相关伤害的风险。

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