Institute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
Eur J Ophthalmol. 2020 Nov;30(6):NP5-NP6. doi: 10.1177/1120672119855845. Epub 2019 Jun 13.
Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it.
The case of a 47-year-old woman showing acute onset of diplopia with bilateral upward gaze palsy is described. Parinaud syndrome was suspected on clinical grounds. However, brain magnetic resonance imaging displayed an acute ischemic lesion in the right anteromedial thalamus.
Bilateral upward gaze palsy may be caused by unilateral thalamic infarction. The mechanism by which a unilateral thalamic lesion causes bilateral gaze palsy is discussed.
中脑梗死引起的 Parinaud 综合征通常表现为眼球同向垂直运动障碍。然而,这一征象并不能直接指向 Parinaud 综合征,因为中枢神经系统的其他病变也可能导致这种情况。
本文报道了一例 47 岁女性,表现为双眼复视伴双眼向上凝视无力。临床上怀疑为 Parinaud 综合征。然而,脑磁共振成像显示右侧前内侧丘脑急性缺血性病变。
双眼向上凝视无力可能是单侧丘脑梗死引起的。讨论了单侧丘脑病变导致双眼凝视无力的机制。