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通过细菌检测将德国血小板浓缩物的储存期延长至5天:这值得付出努力吗?

Extension of the Storage Period of Platelet Concentrates in Germany to 5 Days by Bacterial Testing: Is it Worth the Effort?

作者信息

Vollmer Tanja, Hinse Dennis, Diekmann Jürgen, Knabbe Cornelius, Dreier Jens

机构信息

Herz- und Diabeteszentrum Nordrhein-Westfalen, Institut für Laboratoriums- und Transfusionsmedizin, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany.

出版信息

Transfus Med Hemother. 2019 Apr;46(2):111-113. doi: 10.1159/000499543. Epub 2019 Mar 14.

Abstract

The shelf life of platelet concentrates (PCs) was limited in Germany to 4 days after the day of production because platelet-related septic complications had been observed, mainly with PCs at the end of their shelf life. The reduction in PC shelf life gives rise to several problems, including an increased number of discarded products, accompanied by potential challenges of how to ensure an adequate supply of platelet products. The aim of this study was to show routine experience over the last 7 years using the Bactiflow (BF) assay to screen for bacterial contamination late in PC storage, followed by extension of PC shelf life.

摘要

在德国,由于观察到血小板相关的败血症并发症,主要发生在血小板浓缩物(PCs)保质期快结束时,血小板浓缩物的保质期被限制在生产日之后4天。血小板浓缩物保质期的缩短引发了几个问题,包括废弃产品数量增加,同时还面临如何确保血小板产品充足供应的潜在挑战。本研究的目的是展示过去7年使用Bactiflow(BF)检测法在血小板浓缩物储存后期筛查细菌污染,随后延长血小板浓缩物保质期的常规经验。

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