伊朗法尔斯省奶牛繁殖期葡萄糖、非酯化脂肪酸、β-羟基丁酸和甲状腺激素的田间研究

A field study on glucose, non-esterified fatty acids, beta-hydroxybutyrate and thyroid hormones in dairy cows during the breeding period in Fars province, Iran.

作者信息

Mohebbi-Fani M, Omidi A, Mirzaei A, Nazifi S, Nowroozi Kh

机构信息

Department of Animal Health Management, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

Department of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

出版信息

Iran J Vet Res. 2019 Winter;20(1):55-59.

PMID:31191701

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6509905/

Abstract

BACKGROUND

It was hypothesized that under apparently good management practices in dairy farms, some cows may not be metabolically perfect during the breeding period and this may affect their performance.

AIMS

This study was conducted to assess probable metabolic drawbacks in mid-lactation dairy cows affecting their performance.

METHODS

Thirty-seven clinically healthy Holstein cows were assessed for plasma concentrations of glucose, non-esterified fatty acids (NEFA), beta-hydroxybutyrate (BHB), thyroxin (T4), and tri-iodothyronine (T3) on days 60, 90 and 120 of lactation. The relationships of the measured analytes with some performance indices were also studied.

RESULTS

Continuous declines in plasma glucose (within reference values; P<0.006), T4 (P<0.001) and T3 (0.003) were found during the study. Non-esterified fatty acids showed relatively high levels through the study with a rise at day 90 (P<0.041). Beta-hydroxybutyrate concentrations did not change significantly (P>0.05) but were higher than those reported by others in mid-lactation cows. By progress in lactation 27% of cows had glucose concentrations <2.5 mmol/L, 62% had NEFA concentrations >0.40 mmol/L and 13.5% had BHB levels above 1200 µmol/L, which are the threshold levels of peri- and post-parturient problems. Milk production had negative correlations with glucose and T4 while the correlation was positive with NEFA. The interval between calving to the 1st heat had positive correlations with BHB concentrations. The interval between calving and the 1st insemination was inversely correlated with glucose and positively correlated with NEFA levels.

CONCLUSION

The changes of the studied analytes in mid-lactation cows resembled those that would happen during negative energy balance in early lactation cows and feed restriction in mid-lactation cows and may affect the general health and the performance of the cows.

摘要

背景

据推测，在奶牛场看似良好的管理措施下，一些奶牛在繁殖期可能并非处于代谢完美状态，这可能会影响它们的生产性能。

目的

本研究旨在评估泌乳中期奶牛可能存在的影响其生产性能的代谢缺陷。

方法

在泌乳期的第60天、90天和120天，对37头临床健康的荷斯坦奶牛的血浆葡萄糖、非酯化脂肪酸（NEFA）、β-羟丁酸（BHB）、甲状腺素（T4）和三碘甲状腺原氨酸（T3）浓度进行了评估。还研究了所测分析物与一些生产性能指标之间的关系。

结果

在研究期间发现血浆葡萄糖（在参考值范围内；P<0.006）、T4（P<0.001）和T3（0.003）持续下降。在整个研究过程中，非酯化脂肪酸水平相对较高，在第90天有所上升（P<0.041）。β-羟丁酸浓度没有显著变化（P>0.05），但高于其他报道的泌乳中期奶牛的浓度。随着泌乳进程，27%的奶牛葡萄糖浓度<2.5 mmol/L，62%的奶牛非酯化脂肪酸浓度>0.40 mmol/L，13.5%的奶牛β-羟丁酸水平高于1200 µmol/L，这些都是围产期和产后问题的阈值水平。产奶量与葡萄糖和T4呈负相关，与非酯化脂肪酸呈正相关。产犊至首次发情的间隔与β-羟丁酸浓度呈正相关。产犊与首次输精的间隔与葡萄糖呈负相关，与非酯化脂肪酸水平呈正相关。