Bouwense Stefan A W, Kempeneers Marinus A, van Santvoort Hjalmar C, Boermeester Marja A, van Goor Harry, Besselink Marc G
Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Surgery, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Visc Med. 2019 Apr;35(2):110-118. doi: 10.1159/000499612. Epub 2019 Apr 4.
Chronic pancreatitis is a chronic inflammation of the pancreas with pain as its severest symptom and often an impaired quality of life. Surgical intervention plays an important role in the management of pain but is generally kept as a last resort when conservative measures and endoscopy have failed. However, in the last few years multiple studies suggested the superiority of (early) surgical treatment in chronic pancreatitis for multiple end points, including pain relief. In this paper we highlight the most recent high-quality evidence on surgical therapy in chronic pancreatitis and the rationale for early (surgical) intervention.
慢性胰腺炎是胰腺的一种慢性炎症，疼痛是其最严重的症状，常导致生活质量受损。手术干预在疼痛管理中起着重要作用，但通常在保守措施和内镜检查均失败时才作为最后的手段。然而，在过去几年中，多项研究表明，（早期）手术治疗在慢性胰腺炎的多个终点方面具有优势，包括缓解疼痛。在本文中，我们重点介绍了慢性胰腺炎手术治疗的最新高质量证据以及早期（手术）干预的理论依据。
