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Solving the Opioid Crisis: Respiratory Depression by Opioids as Critical End Point.

作者信息

Montandon Gaspard, Slutsky Arthur S

机构信息

Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

Chest. 2019 Oct;156(4):653-658. doi: 10.1016/j.chest.2019.05.015. Epub 2019 Jun 10.

DOI:10.1016/j.chest.2019.05.015

PMID:31194974

Abstract

摘要

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Solving the Opioid Crisis: Respiratory Depression by Opioids as Critical End Point.

作者信息

Montandon Gaspard, Slutsky Arthur S

机构信息

Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada; Department of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

Chest. 2019 Oct;156(4):653-658. doi: 10.1016/j.chest.2019.05.015. Epub 2019 Jun 10.

DOI:10.1016/j.chest.2019.05.015

PMID:31194974

Abstract

摘要

相似文献

Solving the Opioid Crisis: Respiratory Depression by Opioids as Critical End Point.

Chest. 2019 Oct;156(4):653-658. doi: 10.1016/j.chest.2019.05.015. Epub 2019 Jun 10.

A rural perspective on the opioid crisis.

Nurs Manage. 2019 Aug;50(8):6. doi: 10.1097/01.NUMA.0000575336.16325.45.

Doing Our Part to Mitigate the Opioid Crisis.

Ann Surg Oncol. 2020 Mar;27(3):625-626. doi: 10.1245/s10434-019-08153-6. Epub 2019 Dec 18.

Point-of-Care Drug of Abuse Testing in the Opioid Epidemic.

Arch Pathol Lab Med. 2020 Nov 1;144(11):1325-1334. doi: 10.5858/arpa.2020-0055-RA.

Opioids.

Nature. 2019 Sep;573(7773):S1. doi: 10.1038/d41586-019-02681-7.

The opioid crisis: Origins, trends, policies, and the roles of pharmacists.

Am J Health Syst Pharm. 2019 Mar 19;76(7):424-435. doi: 10.1093/ajhp/zxy089.

The escalation of the opioid epidemic due to COVID-19 and resulting lessons about treatment alternatives.

Am J Manag Care. 2020 Jul 1;26(7):e202-e204. doi: 10.37765/ajmc.2020.43386.

Noradrenergic Mechanisms in Fentanyl-Mediated Rapid Death Explain Failure of Naloxone in the Opioid Crisis.

J Pharmacol Exp Ther. 2019 Nov;371(2):453-475. doi: 10.1124/jpet.119.258566. Epub 2019 Sep 6.

Confronting the opioid crisis with basic research in neuropharmacology.

Neuropharmacology. 2020 Apr;166:107972. doi: 10.1016/j.neuropharm.2020.107972. Epub 2020 Jan 17.

Rational Perioperative Opioid Management in the Era of the Opioid Crisis.

Anesthesiology. 2020 Apr;132(4):603-605. doi: 10.1097/ALN.0000000000003166.

引用本文的文献

A qualitative interview study exploring the experiences of pain specialists on prescribing opioids for chronic non-cancer pain.

Sci Rep. 2025 Aug 13;15(1):29672. doi: 10.1038/s41598-025-15113-6.

Mitragynine and 7-Hydroxymitragynine: Bidirectional Effects on Breathing in Rats.

bioRxiv. 2025 May 21:2025.05.16.654392. doi: 10.1101/2025.05.16.654392.

Cannabidiol Protects against the Reinstatement of Oxycodone-Induced Conditioned Place Preference in Adolescent Male but Not Female Rats: The Role of MOR and CB1R.

Int J Mol Sci. 2024 Jun 17;25(12):6651. doi: 10.3390/ijms25126651.

Fact vs. fiction: naloxone in the treatment of opioid-induced respiratory depression in the current era of synthetic opioids.

Front Public Health. 2024 Feb 28;12:1346109. doi: 10.3389/fpubh.2024.1346109. eCollection 2024.

Antinociceptive and anti-inflammatory activity of extracts and α-pyrones isolated from Cantinoa stricta.

Inflammopharmacology. 2024 Apr;32(2):1263-1275. doi: 10.1007/s10787-024-01444-9. Epub 2024 Mar 11.

Epidemiological Aspects of Opioid Poisoning in Northern Iran: A Registry-Based Clinical Study.

Health Serv Insights. 2024 Feb 22;17:11786329241232300. doi: 10.1177/11786329241232300. eCollection 2024.

βγ G-proteins, but not regulators of G-protein signaling 4, modulate opioid-induced respiratory rate depression.

Front Physiol. 2023 Apr 6;14:1043581. doi: 10.3389/fphys.2023.1043581. eCollection 2023.

Current research in pathophysiology of opioid-induced respiratory depression, neonatal opioid withdrawal syndrome, and neonatal antidepressant exposure syndrome.

Curr Res Toxicol. 2022 Jun 6;3:100078. doi: 10.1016/j.crtox.2022.100078. eCollection 2022.

Sleep Deficiency and Opioid Use Disorder: Trajectory, Mechanisms, and Interventions.

Clin Chest Med. 2022 Jun;43(2):e1-e14. doi: 10.1016/j.ccm.2022.05.001.

Opioid Use Disorder, Sleep Deficiency, and Ventilatory Control: Bidirectional Mechanisms and Therapeutic Targets.

Am J Respir Crit Care Med. 2022 Oct 15;206(8):937-949. doi: 10.1164/rccm.202108-2014CI.

Solving the Opioid Crisis: Respiratory Depression by Opioids as Critical End Point.

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Solving the Opioid Crisis: Respiratory Depression by Opioids as Critical End Point.

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