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从全球角度看燃煤电厂与肺癌负担方面,人群归因分数(PAF)计算有误的问题。

Issues with incorrect computing of population attributable fraction (PAF) in a global perspective on coal-fired power plants and burden of lung cancer.

机构信息

Department of Epidemiology, School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.

Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Environ Health. 2019 Jun 13;18(1):54. doi: 10.1186/s12940-019-0490-6.

DOI:10.1186/s12940-019-0490-6
PMID:31196121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6567379/
Abstract

All observational studies are liable to confounding and Levin's formula becomes useless in practice for unbiasedly estimating PAF. With respect to causal interpretation of PAF in public health setting, unbiased estimation of PAF requires several assumptions which are ignored in practice. We recommend using Miettinen PAF formula with careful consideration about possibility of bias in study design and analysis.

摘要

所有观察性研究都容易受到混杂因素的影响,因此莱文公式在实际中无法用于无偏估计 PAF。在公共卫生环境中对 PAF 的因果解释方面,无偏估计 PAF 需要一些假设,而这些假设在实践中往往被忽略。我们建议使用米滕纳 PAF 公式,并仔细考虑研究设计和分析中可能存在的偏倚。

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引用本文的文献

1
Bias assessment and correction for Levin's population attributable fraction in the presence of confounding.存在混杂时 Levin 人群归因分数的偏差评估和校正。
Eur J Epidemiol. 2024 Feb;39(2):111-119. doi: 10.1007/s10654-023-01063-8. Epub 2024 Jan 3.
2
Population attributable fraction in textbooks: Time to revise.教科书中的人群归因分数:是时候修订了。
Glob Epidemiol. 2021 Aug 28;3:100062. doi: 10.1016/j.gloepi.2021.100062. eCollection 2021 Nov.
3
Estimation and application of population attributable fraction in ecological studies.人群归因分数在生态研究中的估计和应用。
Environ Health. 2019 Jun 13;18(1):52. doi: 10.1186/s12940-019-0492-4.

本文引用的文献

1
A global perspective on coal-fired power plants and burden of lung cancer.全球视角下的燃煤电厂与肺癌负担。
Environ Health. 2019 Jan 28;18(1):9. doi: 10.1186/s12940-019-0448-8.
2
Population attributable fraction.人群归因分数。
BMJ. 2018 Feb 22;360:k757. doi: 10.1136/bmj.k757.
3
Commentary: Errors in estimating adjusted attributable fractions.评论:调整归因分数估计中的误差。
Epidemiology. 2014 Nov;25(6):917-8. doi: 10.1097/EDE.0000000000000177.
4
Ecological studies: advantages and disadvantages.生态学研究:优点与缺点。
BMJ. 2014 May 2;348:g2979. doi: 10.1136/bmj.g2979.
5
Confounding and bias in the attributable fraction.归因分数中的混杂和偏倚。
Epidemiology. 2011 Jan;22(1):53-8. doi: 10.1097/EDE.0b013e3181fce49b.