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豚鼠颈动脉窦压力感受器及肾上腺素能神经支配的精细结构观察

Observations on the fine structure of the baroreceptors and adrenergic innervation of the guinea-pig carotid sinus.

作者信息

Shin H S, Hulbert W C, Biggs D F

机构信息

Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.

出版信息

J Morphol. 1987 Oct;194(1):65-74. doi: 10.1002/jmor.1051940106.

DOI:10.1002/jmor.1051940106
PMID:3119863
Abstract

We examined the fine structure of the baroreceptors and the adrenergic innervation of the guinea-pig carotid sinus. The tunica adventitia contained many nerve bundles whose perineuria enclosed unmyelinated nerve fibers, alone or together with myelinated nerve fibers. Baroreceptors, which lay close to elastic and collagen fibers in the adventitia and media, were surrounded by "terminal" cells with ultrastructural features characteristic of Schwann cells and contained inclusions of various types. Morphologic features of the baroreceptors included densely packed mitochondria, osmiophilic lamellated and homogeneous bodies, clear and granular vesicles, lamellar systems, glycogen granules, neurofilaments, neurotubuli, and vacuolated mitochondria. In animals that had been treated with 6-hydroxydopamine, occasional electron-dense endings (or fibers) were observed in the adventitial layer. The baroreceptors in the guinea-pig carotid sinus appear to have most of the morphologic features reported for other species.

摘要

我们研究了豚鼠颈动脉窦压力感受器的精细结构及其肾上腺素能神经支配。外膜中有许多神经束,其神经束膜包绕着无髓神经纤维,这些无髓神经纤维可单独存在,也可与有髓神经纤维共存。压力感受器位于外膜和中膜的弹性纤维和胶原纤维附近,被具有施万细胞超微结构特征的“终末”细胞所包围,并含有各种类型的内含物。压力感受器的形态学特征包括紧密排列的线粒体、嗜锇层状和均质小体、清亮和颗粒状囊泡、层状系统、糖原颗粒、神经丝、神经微管以及空泡化线粒体。在用6-羟基多巴胺处理过的动物中,在外膜层偶尔可见电子致密的终末(或纤维)。豚鼠颈动脉窦中的压力感受器似乎具有其他物种所报道的大多数形态学特征。

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