Kimura I, Kimura M, Kimura M
Department of Chemical Pharmacology, Faculty of Pharmaceutical Science, Toyama Medical and Pharmaceutical University, Japan.
Jpn J Pharmacol. 1987 Aug;44(4):510-4. doi: 10.1254/jjp.44.510.
Intracellular Ca2+ release in directly stimulated diaphragm muscles of mice was found to be dependent on external Ca2+, using the intracellular Ca2+ aequorin luminescence transient technique. The Ca2+ mobilization into the cells may operate via a voltage- and external Ca2+-dependent mechanism, and via a caffeine- and external Ca2+-independent one, from the Ca2+ pools in plasma membranes or in the terminal cisternae of sarcoplasmic reticulum.
利用细胞内水母发光蛋白钙瞬变技术发现，直接刺激的小鼠膈肌中的细胞内钙释放依赖于细胞外钙。钙流入细胞可能通过一种电压和细胞外钙依赖性机制，以及一种咖啡因和细胞外钙非依赖性机制，从质膜或肌浆网终末池中的钙库进行。
