在研抗菌药物及近期展望。
Antibacterials in the pipeline and perspectives for the near future.
机构信息
Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZN, United Kingdom; University of Aberdeen, Aberdeen, United Kingdom.
Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZN, United Kingdom; University of Colombo, Colombo, Sri Lanka.
出版信息
Curr Opin Pharmacol. 2019 Oct;48:69-75. doi: 10.1016/j.coph.2019.05.001. Epub 2019 Jun 11.
Antimicrobial resistance is a global threat to the management of infections in our patients. Sound stewardship of antibacterial agents at our disposal must be accompanied by a concerted effort to develop new agents to bolster our armamentarium. This review will cover the latest antibiotics that have come through the pipeline and the role they can play in the management of infections that are increasingly difficult to treat due to resistance mechanisms.
抗菌药物耐药性是全球范围内对我们患者感染管理的威胁。在合理使用现有抗菌药物的同时，必须齐心协力开发新的药物来增强我们的武器库。这篇综述将介绍最新的抗生素，以及它们在治疗由于耐药机制而变得越来越难以治疗的感染方面的作用。
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