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在撒哈拉以南非洲实施“全面治疗”时代改善艾滋病毒护理衔接的干预措施:系统评价。

Interventions to Improve Linkage to HIV Care in the Era of "Treat All" in Sub-Saharan Africa: a Systematic Review.

机构信息

University of California, 2121 Berkeley Way, MC 7360, Berkeley, CA, 94720, USA.

Community Development, Gender, Elderly, and Children, Ministry of Health, Dar es Salaam, Tanzania.

出版信息

Curr HIV/AIDS Rep. 2019 Aug;16(4):292-303. doi: 10.1007/s11904-019-00451-8.


DOI:10.1007/s11904-019-00451-8
PMID:31201613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10655251/
Abstract

PURPOSE OF THE REVIEW: In 2015, antiretroviral therapy (ART) was recommended for all people living with HIV (PLHIV) regardless of CD4 count ("Treat All"). To better understand how to improve linkage to care under these new guidelines, we conducted a systematic review of studies evaluating linkage interventions in Sub-Saharan Africa under Treat All. RECENT FINDINGS: We identified 14 eligible articles and qualitatively analyzed the effectiveness of the interventions. Increases in linkage were reported by supply-side and counseling interventions. Mobile testing and economic incentives did not increase linkage. Given the lag time between adoption and implementation, only two of the studies were conducted in a Treat All setting. None of the interventions specifically focused on re-linking PLHIV who had disengaged from care. Future studies must design interventions that target not only newly diagnosed or treatment naïve PLHIV, but should explicitly focus on PLHIV who have disengaged from care.

摘要

目的综述:2015 年,抗逆转录病毒疗法(ART)被推荐用于所有艾滋病毒感染者(PLHIV),无论 CD4 计数如何(“全面治疗”)。为了更好地了解如何在这些新指南下改善护理衔接,我们对撒哈拉以南非洲地区在“全面治疗”下评估衔接干预措施的研究进行了系统评价。

最新发现:我们确定了 14 篇合格的文章,并对干预措施的有效性进行了定性分析。供应方干预和咨询干预措施报告了衔接率的提高。移动检测和经济激励措施并没有增加联系。鉴于采用和实施之间的时间滞后,只有两项研究是在“全面治疗”环境中进行的。这些干预措施都没有专门针对已经脱离护理的 PLHIV 重新建立联系。未来的研究必须设计针对新诊断或初次治疗的 PLHIV 的干预措施,并且应该明确关注已经脱离护理的 PLHIV。

相似文献

[1]
Interventions to Improve Linkage to HIV Care in the Era of "Treat All" in Sub-Saharan Africa: a Systematic Review.

Curr HIV/AIDS Rep. 2019-8

[2]
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J Int AIDS Soc. 2014-8-1

[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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HIV AIDS (Auckl). 2019-12-2

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[2]
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[3]
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Trials. 2024-2-10

[4]
Rudi Kundini, Pamoja Kundini (RKPK): study protocol for a hybrid type 1 randomized effectiveness-implementation trial using data science and economic incentive strategies to strengthen the continuity of care among people living with HIV in Tanzania.

Res Sq. 2023-12-20

[5]
Attrition one year after starting antiretroviral therapy before and after the programmatic implementation of HIV "Treat All" in Sub-Saharan Africa: a systematic review and meta-analysis.

BMC Infect Dis. 2023-8-28

[6]
Advanced HIV disease and associated attrition after re-engagement in HIV care in Myanmar from 2003 to 2019: a retrospective cohort study.

Int Health. 2023-7-4

[7]
Barriers and facilitators on the HIV care continuum among adults living with HIV in high-income countries: a scoping review protocol.

Syst Rev. 2022-10-15

[8]
Financial incentives to improve re-engagement in HIV care: results from a randomized pilot study.

AIDS Care. 2023-7

[9]
How does HIV testing modality impact the cascade of care among persons diagnosed with HIV in Ethiopia?

Glob Health Action. 2021-1-1

[10]
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本文引用的文献

[1]
Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA).

J Int AIDS Soc. 2019-1

[2]
Effect of a Patient-Centered Phone Call by a Clinical Officer at Time of HIV Testing on Linkage to Care in Rural Kenya.

Open Forum Infect Dis. 2018-5-29

[3]
Effect of Offering Same-Day ART vs Usual Health Facility Referral During Home-Based HIV Testing on Linkage to Care and Viral Suppression Among Adults With HIV in Lesotho: The CASCADE Randomized Clinical Trial.

JAMA. 2018-3-20

[4]
A Conditional Economic Incentive Fails to Improve Linkage to Care and Antiretroviral Therapy Initiation Among HIV-Positive Adults in Cape Town, South Africa.

AIDS Patient Care STDS. 2018-2

[5]
A combination intervention strategy to improve linkage to and retention in HIV care following diagnosis in Mozambique: A cluster-randomized study.

PLoS Med. 2017-11-14

[6]
Effectiveness of a combination strategy for linkage and retention in adult HIV care in Swaziland: The Link4Health cluster randomized trial.

PLoS Med. 2017-11-7

[7]
Brief counselling after home-based HIV counselling and testing strongly increases linkage to care: a cluster-randomized trial in Uganda.

J Int AIDS Soc. 2017-10

[8]
Expanding HIV testing and linkage to care in southwestern Uganda with community health extension workers.

J Int AIDS Soc. 2017-7-21

[9]
Effect of point-of-care CD4 cell count results on linkage to care and antiretroviral initiation during a home-based HIV testing campaign: a non-blinded, cluster-randomised trial.

Lancet HIV. 2017-5-31

[10]
Strategies to Accelerate HIV Care and Antiretroviral Therapy Initiation After HIV Diagnosis: A Randomized Trial.

J Acquir Immune Defic Syndr. 2017-8-15

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