Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Department of Surgery, University of Minnesota, Minneapolis, Minnesota.
Surg Obes Relat Dis. 2019 Jul;15(7):1146-1152. doi: 10.1016/j.soard.2019.04.028. Epub 2019 May 2.
Bariatric surgery patients are at risk for vitamin deficiencies.
Investigate the prevalence of deficiencies of vitamins A, B1, B12, D, and folate in sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) patients in a single institution.
An academic medical center.
Retrospective chart reviews of 468 bariatric surgery patients (358 SG and 110 RYGB) were analyzed for vitamin levels, calcium, and parathyroid hormone. Both preoperative and postoperative measurements were obtained.
Deficiency of vitamin D was the most common, seen in 27% preoperatively. Postoperatively, RYGB patients had a higher prevalence of vitamin D deficiency than SG patients (11.5% RYGB versus 5.2% SG within the first postoperative year, and 20.3% RYGB versus 13.4% SG after 1 year). Elevated parathyroid hormone was observed in 45% of RYGB patients after 1 year postoperatively. Vitamin A deficiency was uncommon preoperatively (2.7% SG versus 1.7% RYGB), but increased after surgery (9.4% SG versus 15.9% RYGB within 1 year postoperatively, and 5.2% SG versus 7.7% RYGB after 1 year). Vitamin B1 deficiency was observed in 8.1% SG versus 1.7% RYGB patients preoperatively and increased during the first year postoperatively (SG 10.5% and RYGB 13.7%), but improved after 1 year (7.2% SG versus 5.9% RYGB). Less than 2% of Vitamin B12 deficiencies and no folate deficiencies occurred in both SG and RYGB patients.
The highest prevalence of vitamin B1 and A deficiencies were seen in the first year postoperatively. Vitamin B12 and folate deficiency were uncommon in our patients. Vitamin D deficiency improved after surgery, but elevated parathyroid hormone was common after RYGB.
减重手术患者存在维生素缺乏的风险。
在一家医疗机构中，调查袖状胃切除术（SG）和 Roux-en-Y 胃旁路术（RYGB）患者中维生素 A、B1、B12、D 和叶酸缺乏的发生率。
一家学术医疗中心。
对 468 例减重手术患者（358 例 SG 和 110 例 RYGB）的病历进行回顾性分析，以评估维生素水平、钙和甲状旁腺激素。获取术前和术后的测量值。
维生素 D 缺乏是最常见的，术前发生率为 27%。术后，RYGB 患者维生素 D 缺乏的发生率高于 SG 患者（术后 1 年内，RYGB 组为 11.5%，SG 组为 5.2%；术后 1 年以上，RYGB 组为 20.3%，SG 组为 13.4%）。术后 1 年，45%的 RYGB 患者甲状旁腺激素升高。术前维生素 A 缺乏不常见（SG 组为 2.7%，RYGB 组为 1.7%），但术后增加（术后 1 年内，SG 组为 9.4%，RYGB 组为 15.9%；术后 1 年以上，SG 组为 5.2%，RYGB 组为 7.7%）。术前 SG 组和 RYGB 组分别有 8.1%和 1.7%的患者存在维生素 B1 缺乏，术后第 1 年增加（SG 组为 10.5%，RYGB 组为 13.7%），但术后 1 年改善（SG 组为 7.2%，RYGB 组为 5.9%）。SG 和 RYGB 患者中维生素 B12 和叶酸缺乏的发生率均低于 2%。
术后第 1 年，维生素 B1 和 A 缺乏的发生率最高。维生素 B12 和叶酸缺乏在我们的患者中并不常见。维生素 D 缺乏在手术后得到改善，但 RYGB 后甲状旁腺激素升高很常见。
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