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土耳其哈塔伊省输入性疟疾病例的回顾性分析:十年间75例病例

Retrospective Analysis of Cases with Imported Malaria in Hatay Province of Turkey: Seventy-Five Cases in Ten Years.

作者信息

Şahin Selma İlkay, Çabalak Mehmet, Bal Tayibe, Ocak Sabahattin, Önlen Yusuf, Çulha Gülnaz

机构信息

Nusaybin Devlet Hastanesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Mardin, Türkiye

Hatay Mustafa Kemal Üniversitesi, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye

出版信息

Turkiye Parazitol Derg. 2019 Jun 17;43(2):60-64. doi: 10.4274/tpd.galenos.2019.6123.

Abstract

OBJECTIVE

Cases with imported malaria have increased complication and mortality rates because of delayed diagnosis and treatment in non-endemic countries. This study aimed to investigate the incidence and clinical features of imported malaria in our clinic during the past 10 years.

METHODS

This retrospective study included 75 cases diagnosed as having imported malaria in our clinic between January 2008 and December 2017. The epidemiological data, laboratory findings, treatment data and clinical course of the cases were obtained from system records.

RESULTS

Patients were predominantly male (%98.6) with a median age of 51 (23-64) years. All cases were infected with , had a recent travel history to Sub-Saharan African countries and none had received chemoprophylaxis before travel. The incidence of imported malaria showed a declining trend after 2015. The most common findings were fever (100%), thrombocytopenia (84%) and anemia (72%). Although 8% of patients had presented with severe malaria, none of them died.

CONCLUSION

Despite increasing incidence of imported malaria in our country in recent years, there is a decrease in this number in our region. Since Turkey is one of the countries with the highest prevalence of imported malaria in the world, patients with fever and thrombocytopenia should be questioned whether or not they had a history of travel to malaria-endemic area.

摘要

目的

由于非疟疾流行国家的诊断和治疗延误,输入性疟疾病例的并发症和死亡率有所增加。本研究旨在调查过去10年我院输入性疟疾的发病率和临床特征。

方法

这项回顾性研究纳入了2008年1月至2017年12月期间在我院诊断为输入性疟疾的75例病例。病例的流行病学数据、实验室检查结果、治疗数据和临床病程均从系统记录中获取。

结果

患者以男性为主(98.6%),中位年龄为51岁(23 - 64岁)。所有病例均感染 ,近期有前往撒哈拉以南非洲国家的旅行史,且无一例在旅行前接受过化学预防。2015年后输入性疟疾的发病率呈下降趋势。最常见的表现为发热(100%)、血小板减少(84%)和贫血(72%)。虽然8%的患者出现了重症疟疾,但无一例死亡。

结论

尽管近年来我国输入性疟疾的发病率有所上升,但我们地区的这一数字有所下降。由于土耳其是世界上输入性疟疾患病率最高的国家之一,对于发热和血小板减少的患者,应询问其是否有前往疟疾流行地区的旅行史。

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