Corbett Blythe A, Blain Scott D, Kale Edmiston E
Vanderbilt University, Department of Psychiatry.
Vanderbilt University, Department of Psychology.
J Intellect Dev Disabil. 2018;43(1):20-28. doi: 10.3109/13668250.2017.1310824. Epub 2017 May 28.
Autism Spectrum Disorder (ASD) is characterised by altered social patterns, often associated with increased stress. While puberty is associated with increased stress, there is limited research on stress response to in adolescents with ASD. The study investigated stress response to semi-structured, videogame-based interaction in adolescents with and without ASD, and the impact of puberty.
Twelve adolescents with ASD and 12 typically developing (TD) peers participated in a semi-structured, videogame-based . Stress was measured via salivary cortisol.
There were no significant between-group differences in cortisol. Pubertal development was correlated with cortisol in ASD (r = -0.901, p < 0.0001), but not TD (r = 0.022, p = 0.949).
Findings contribute to a fuller picture of the developmental trajectories of physiological stress in ASD, including the importance of context, structure, and puberty. The current investigation underscores the necessity of incorporating varied social contexts when assessing stress and .
自闭症谱系障碍（ASD）的特征是社交模式改变，常伴有压力增加。虽然青春期与压力增加有关，但关于ASD青少年应激反应的研究有限。该研究调查了有和没有ASD的青少年对半结构化、基于电子游戏的互动的应激反应，以及青春期的影响。
12名患有ASD的青少年和12名发育正常（TD）的同龄人参与了一项半结构化、基于电子游戏的……。通过唾液皮质醇测量压力。
两组之间的皮质醇没有显著差异。青春期发育与ASD中的皮质醇相关（r = -0.901，p < 0.0001），但与TD无关（r = 0.022，p = 0.949）。
研究结果有助于更全面地了解ASD中生理压力的发展轨迹，包括背景、结构和青春期的重要性。当前的调查强调了在评估压力和……时纳入不同社交背景的必要性。
