Pérez-Surio Alberto Frutos, Ortiz Roberto Lozano, Crespo Alejandro Martínez
Department of Clinical Pharmacy, University Clinical Hospital Lozano Blesa, Zaragoza, Spain.
Department of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, Spain.
JRSM Cardiovasc Dis. 2019 May 24;8:2048004019848273. doi: 10.1177/2048004019848273. eCollection 2019 Jan-Dec.
To evaluate the risk of having a stroke and the risk of bleeding in institutionalized patients with atrial fibrillation. Atrial fibrillation is a common cardiac arrhythmia associated with increased morbidity and mortality. It is necessary to develop pharmacotherapy plans to minimize the risk.
A prospective study.
Institutionalized patients.
Inclusion criteria were: patients diagnosed with atrial fibrillation, with or without treatment for the prevention of stroke.
The evaluation of the CHA2DS2-VASc criteria was performed. The risk of hemorrhage was assessed using the HAS-BLED scale, based on the risk factors associated with the probability of bleeding.
We included 53 patients (86.4 ± 6.4 years, 30.2% men). Of these, 37 (69.8%) were correctly anticoagulated. Of the remaining, 5 patients (31.2%) did not have any type of anticoagulant or antiaggregant treatment and 11 (68.7%) were treated with antiaggregant alone. The pharmaceutical intervention was performed in patients who did not meet stroke criteria. Of the untreated patients: two died before the intervention, two were recommended to be referred to cardiology and in one there was no intervention because of very advanced age. In the antiaggregant patients, it was decided not to modify the treatment. The reasons were: high risk of bleeding, very advanced age, advanced dementia or terminal illness, moderate risk of stroke, and clotting factor deficiency.
The risk of stroke in elderly patients with atrial fibrillation is high, so it is important to control the risk factors.
评估入住机构的心房颤动患者发生中风的风险及出血风险。心房颤动是一种常见的心律失常,与发病率和死亡率增加相关。制定药物治疗方案以将风险降至最低很有必要。
一项前瞻性研究。
入住机构的患者。
纳入标准为:诊断为心房颤动的患者,无论是否接受过预防中风的治疗。
对CHA2DS2-VASc标准进行评估。基于与出血可能性相关的危险因素,使用HAS-BLED量表评估出血风险。
我们纳入了53例患者(86.4±6.4岁,男性占30.2%)。其中,37例(69.8%)接受了正确的抗凝治疗。其余患者中,5例(31.2%)未接受任何类型的抗凝或抗血小板治疗,11例(68.7%)仅接受了抗血小板治疗。对不符合中风标准的患者进行了药物干预。在未治疗的患者中:2例在干预前死亡,2例被建议转诊至心脏病科,1例因年龄过大未进行干预。在接受抗血小板治疗的患者中,决定不改变治疗方案。原因包括:出血风险高、年龄过大、晚期痴呆或终末期疾病、中风风险中等以及凝血因子缺乏。
老年心房颤动患者中风风险高,因此控制危险因素很重要。