Lee Yong Hoon, Seo Hyewon, Cha Seung Ick, Kim Chang Ho, Lee Jaehee
Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Ann Transl Med. 2019 May;7(9):205. doi: 10.21037/atm.2019.03.70.
Pseudomembranous tracheitis (PMT) is a rare condition characterized by pseudomembrane formation in the tracheobronchial tree that may be associated with infectious and noninfectious processes. However, PMT attributed to (), a common atypical respiratory infectious pathogen, has not been reported till date. Here, we report about a 29-year-old woman with complaints of severe persistent cough and radiographic deterioration despite antibiotics administration for pneumonia at an outside facility. She was finally diagnosed as having PMT with bilateral diffuse bronchiolitis caused by infection. The diagnosis was made based on a bronchoscopic finding of a pseudomembrane that partially covered the membranous portion of the upper and middle trachea, a positive polymerase chain reaction (PCR) test with bronchial aspirate, and a positive serological test for without detection of any other causative pathogen through an extensive workup. Her symptoms and radiographic findings improved in response to moxifloxacin and corticosteroid treatment. This case is a rare presentation of infection complicating PMT in a young adult without any known risk factors.
假膜性气管支气管炎(PMT)是一种罕见疾病,其特征为气管支气管树中形成假膜,可能与感染性和非感染性过程相关。然而,由常见的非典型呼吸道感染病原体()引起的PMT迄今尚未见报道。在此,我们报告一名29岁女性,在外院因肺炎接受抗生素治疗后仍主诉严重持续性咳嗽且影像学表现恶化。她最终被诊断为患有由()感染引起的双侧弥漫性细支气管炎的PMT。诊断依据为支气管镜检查发现假膜部分覆盖上、中气管的膜部,支气管吸出物聚合酶链反应(PCR)检测呈阳性,以及血清学检测针对()呈阳性,且通过全面检查未检测到任何其他致病病原体。她的症状和影像学表现经莫西沙星和皮质类固醇治疗后有所改善。该病例是在无任何已知危险因素的年轻成年人中罕见的()感染并发PMT的表现。