This paper serves as the lead article introducing the special section of the Journal of Research on Adolescence focused on processes of religious and spiritual influence during adolescence. The purpose of the special section is to review prior theory and research on the processes by which religiosity and spirituality might influence youth outcomes, present original cutting-edge theory and research on processes of religious and spiritual influence, and point to the most fruitful directions and methodological approaches for future work in the area. The special section is guided by eight research questions which push researchers to go beyond mere bivariate associations between religion/spirituality and youth outcomes to unpacking the processes of influence at work.