[脓毒症患儿新发器官功能障碍的特征]
[Features of new-onset organ dysfunction in children with sepsis].
作者信息
Yang Yu-Hang, Pei Liang, Wang Li-Jie, Xu Wei, Liu Chun-Feng
机构信息
Department of Pediatric Intensive Care Unit, Shengjing Hospital of China Medical University, Shenyang 110004, China.
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jun;21(6):517-521. doi: 10.7499/j.issn.1008-8830.2019.06.004.
OBJECTIVE
To study the features of new-onset organ dysfunction in children with sepsis in the pediatric intensive care unit (PICU).
METHODS
A retrospective analysis was performed for the clinical data of children with sepsis who were admitted to the PICU from 2015 to 2016. There were 34 children with severe sepsis and 69 with non-severe sepsis, and the two groups were compared in terms of the incidence rate of new-onset organ dysfunction and the functional status on admission and at discharge.
RESULTS
The severe sepsis group had a significantly higher incidence rate of new-onset organ dysfunction than the non-severe sepsis group (38% vs 6%; P<0.05). The children in the non-severe sepsis group had a relatively good functional status on admission, with marked improvement in the overall functional status at discharge. The children in the severe sepsis group had a poor functional status on admission, with mild/moderate abnormalities in consciousness, sensation, communication and respiratory function at discharge.
CONCLUSIONS
Children with non-severe sepsis have a low incidence rate of new-onset organ dysfunction and a good prognosis, and those with severe sepsis often have a high incidence rate of new-onset organ dysfunction and a poor prognosis.
目的
研究儿科重症监护病房（PICU）中脓毒症患儿新发器官功能障碍的特征。
方法
对2015年至2016年入住PICU的脓毒症患儿的临床资料进行回顾性分析。其中重度脓毒症患儿34例，非重度脓毒症患儿69例，比较两组新发器官功能障碍的发生率以及入院时和出院时的功能状态。
结果
重度脓毒症组新发器官功能障碍的发生率显著高于非重度脓毒症组（38% 对6%；P<0.05）。非重度脓毒症组患儿入院时功能状态相对较好，出院时整体功能状态有明显改善。重度脓毒症组患儿入院时功能状态较差，出院时意识、感觉、沟通及呼吸功能有轻/中度异常。
结论
非重度脓毒症患儿新发器官功能障碍的发生率低，预后良好；而重度脓毒症患儿新发器官功能障碍的发生率常较高且预后较差。
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