Mal H, Bunel V, Marceau A, Dombret M C, Debray M P, Crestani B
Service de pneumologie B, hôpital Bichat, Assistance publique-Hôpitaux de Paris, 75018 Paris, France; Inserm UMR1152, université Paris7 Denis Diderot, 75018 Paris, France.
Service de pneumologie B, hôpital Bichat, Assistance publique-Hôpitaux de Paris, 75018 Paris, France; Inserm UMR1152, université Paris7 Denis Diderot, 75018 Paris, France.
Rev Mal Respir. 2019 Sep;36(7):880-888. doi: 10.1016/j.rmr.2019.05.039. Epub 2019 Jun 14.
Lung hyperinflation which is a hallmark of advanced emphysema plays a major role in the exertional dyspnoea experienced by patients. This has led to the development of surgical lung volume reduction which, though effective, is also associated with significant morbidity and mortality. The goal of endoscopic lung volume reduction which has developed over several years is to decrease hyperinflation without exposing patients to the risks of surgery. Several endoscopic techniques have been assessed by high quality controlled studies: airway by-pass, instillation of glue, insertion of coils or unidirectional valves, vapour ablation. The aim of this review is to present the results of these studies in terms of functional benefit and side effects. Based on these studies, an algorithm for the endoscopic management of advanced forms of emphysema is proposed.
肺过度充气是晚期肺气肿的一个标志，在患者运动性呼吸困难中起主要作用。这导致了外科肺减容术的发展，尽管该手术有效，但也伴有显著的发病率和死亡率。经过数年发展的内镜下肺减容术的目标是减少肺过度充气，同时避免患者承受手术风险。多项高质量对照研究评估了几种内镜技术：气道旁路术、胶水注入、线圈或单向阀置入、蒸汽消融。本综述的目的是从功能效益和副作用方面介绍这些研究的结果。基于这些研究，提出了一种晚期肺气肿内镜治疗的算法。
Zotero 插件