Bornemann Reinhard, Tillmann Roland
Innere Klinik, Klinikum Bielefeld, Bielefeld, Deutschland.
Arbeitsgruppe 2 Bevölkerungsmedizin und biomedizinische Grundlagen, Fakultät für Gesundheitswissenschaften, Universität Bielefeld, Universitätsstr. 25, 33615, Bielefeld, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2019 Aug;62(8):952-959. doi: 10.1007/s00103-019-02978-y.
Antimicrobial resistance is an increasing problem - a consequence of uncritical use, especially of "last-resort" antibiotics. Approaches towards a more rational use of antibiotics have so far focused on the inpatient sector, whereas the majority of antibiotics are prescribed in the outpatient sector. Therefore, there is demand for innovative approaches for the latter sector. The project Antibiotic Therapy in Bielefeld ("AnTiB"), founded in 2016 by pediatricians active in the outpatient pediatric sector, developed respective structures and measures at the local level.
The development of local recommendations, suitable for everyday practice, for antibiotic prescription in frequent infectious conditions, are described.
In order to develop these recommendations, evidence from the literature and practice guidelines was collected. In a structured process, mainly via quality circles, the contents were consented locally and then put under external expert review. Together with the Association of Statutory Health Insurance Physicians of Westphalia-Lippe (KVWL), antibiotic prescription data were collected exemplarily for 2016.
The first version of the respective pediatric recommendations was published in January 2017. Meanwhile, comparable recommendations for outpatient gynecologists and adult GPs were released. Antibiotic prescription data from 2016 show an important spread of antibiotic prescription prevalences in general as well as with respect to single agent classes.
Locally consented practical recommendations may contribute to a local "culture" of antibiotic prescription behavior. The pediatric recommendations locally have so far gained good coverage and high acceptance. Transfer to other regions or medical disciplines seems possible and reasonable. In the future, the effects of such projects on the prescription behavior will be measurable by the comparison of prescription data.
抗生素耐药性问题日益严重,这是不加区分使用抗生素,尤其是“最后手段”抗生素的结果。迄今为止,促进抗生素合理使用的方法主要集中在住院部门,而大多数抗生素是在门诊部门开具的。因此,门诊部门需要创新方法。比勒费尔德抗生素治疗项目(“AnTiB”)由活跃于门诊儿科领域的儿科医生于2016年创立,在地方层面制定了相应的结构和措施。
描述针对常见感染性疾病抗生素处方制定适用于日常实践的地方建议。
为制定这些建议,收集了文献证据和实践指南。通过一个结构化过程,主要是通过质量改进小组,在当地对内容达成共识,然后提交外部专家评审。与威斯特法伦-利珀法定医疗保险医生协会(KVWL)一起,以2016年为例收集了抗生素处方数据。
相应的儿科建议第一版于2017年1月发布。与此同时,发布了针对门诊妇科医生和成人全科医生的类似建议。2016年的抗生素处方数据显示,总体以及单一药物类别方面,抗生素处方患病率有重要差异。
经当地认可的实用建议可能有助于形成抗生素处方行为的地方“文化”。到目前为止,当地的儿科建议覆盖面广且接受度高。向其他地区或医学学科的推广似乎可行且合理。未来,通过比较处方数据可以衡量此类项目对处方行为的影响。