Marques Renata Sofia Ferreira, Antunes Cristiano, Machado Maria João, Ramos Rui, Duarte Nubélio, Oliveira Leandro, Alegria Carlos, Sousa Nuno
Neurosurgery Department, Hospital de Braga, Braga, Portugal.
Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, 4710-057, Braga, Portugal.
Eur J Trauma Emerg Surg. 2021 Oct;47(5):1461-1466. doi: 10.1007/s00068-019-01172-8. Epub 2019 Jun 17.
Head injury is a frequent reason for admission to the emergency department. In parallel, there is a growing use of anticoagulants in an increasingly aging population, which renders this particular group of trauma patients more frequent. In several countries, including Portugal, a 24-h surveillance period followed by repetition of head computed tomography (CT) is the standard procedure for these patients. However, these recommendations have not been based on studies of prevalence of intracranial hemorrhages in control head CTs, namely in this group of anticoagulated patients. This study intends to evaluate the prevalence of de novo intracranial hemorrhages in control head CTs in anticoagulated patients.
An observational study was carried out, which included patients admitted to Hospital de Braga between June 2017 and January 2018, victims of head injury and on anticoagulation therapy, whose admission head CT excluded intracranial hemorrhage.
We collected a total of 201 patients, with a mean age of 81.6 years, and 57.5% of them were prescribed warfarin; 181 of these patients repeated the head CT 24 h later. Of these 181 patients, 3 (1.66%) exhibited intracranial hemorrhage in control CT, without surgical indication. All patients were followed up 1 month after the trauma, and there was no readmission requiring hospitalization, surgery or death.
In conclusion, de novo intracranial hemorrhage in control head CT of anticoagulated patients is rare. We propose that these patients may be discharged if the admission CT does not reveal intracranial hemorrhage, providing that they are accompanied by a caregiver and informed about red flags.
头部受伤是急诊入院的常见原因。与此同时,在人口老龄化日益严重的情况下,抗凝剂的使用越来越多,这使得这类创伤患者更为常见。在包括葡萄牙在内的几个国家,对这些患者的标准程序是进行24小时监测,随后重复进行头部计算机断层扫描(CT)。然而,这些建议并非基于对照头部CT(即这类接受抗凝治疗的患者)中颅内出血患病率的研究。本研究旨在评估接受抗凝治疗患者对照头部CT中新发颅内出血的患病率。
开展了一项观察性研究,纳入了2017年6月至2018年1月期间因头部受伤而入院且正在接受抗凝治疗、入院时头部CT排除颅内出血的患者。
我们共收集了201例患者,平均年龄为81.6岁,其中57.5%的患者使用华法林;其中181例患者在24小时后重复进行了头部CT检查。在这181例患者中,3例(1.66%)在对照CT中出现颅内出血,但无手术指征。所有患者在创伤后1个月进行了随访,没有再次入院需要住院、手术或死亡的情况。
总之,接受抗凝治疗患者的对照头部CT中新发颅内出血很少见。我们建议,如果入院CT未显示颅内出血,这些患者可以出院,前提是有护理人员陪同并被告知注意事项。