• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

双侧生化隐匿性嗜铬细胞瘤,实则并非隐匿。

Bilateral biochemically silent pheochromocytoma, not silent after all.

作者信息

El-Doueihi Robert Zakhia, Salti Ibrahim, Maroun-Aouad Marie, El Hajj Albert

机构信息

Department of Surgery, American University of Beirut-MC, Beirut, Lebanon.

Department of Internal Medicine, American University of Beirut-MC, Beirut, Lebanon.

出版信息

Urol Case Rep. 2019 Mar 22;24:100876. doi: 10.1016/j.eucr.2019.100876. eCollection 2019 May.

DOI:10.1016/j.eucr.2019.100876
PMID:31211085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6562571/
Abstract

Pheochromocytoma is a sympathetic paraganglioma originating from the chromaffin cells. They are bilateral in 10% of cases and occur as a part of a MEN 2A or 2B syndromes. This is a case of bilateral asymptomatic pheochromocytomas diagnosed incidentally on imaging in a woman being investigated for secondary infertility. Laboratory tests were negative. Whole body FDG scan showed avid uptake of the tracer by both adrenal masses, but none in the thyroid. Hypertensive crisis occurred during right adrenalectomy on an unprepared patient in spite of clamping the adrenal vein, which raises the need for alpha-adrenergic blockade for patients undergoing adrenalectomy.

摘要

嗜铬细胞瘤是一种起源于嗜铬细胞的交感神经节细胞瘤。10%的病例为双侧性,且可作为2A或2B型多发性内分泌腺瘤综合征的一部分出现。这是一例双侧无症状嗜铬细胞瘤的病例,在一名因继发性不孕接受检查的女性患者的影像学检查中偶然发现。实验室检查结果为阴性。全身FDG扫描显示,双侧肾上腺肿块均有放射性示踪剂摄取,但甲状腺未见摄取。尽管在右肾上腺切除术中钳夹了肾上腺静脉,但一名未做准备的患者仍发生了高血压危象,这凸显了对接受肾上腺切除术的患者进行α-肾上腺素能阻滞的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c73/6562571/18f79182253a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c73/6562571/4a19391492ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c73/6562571/18f79182253a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c73/6562571/4a19391492ee/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c73/6562571/18f79182253a/gr2.jpg

相似文献

1
Bilateral biochemically silent pheochromocytoma, not silent after all.双侧生化隐匿性嗜铬细胞瘤,实则并非隐匿。
Urol Case Rep. 2019 Mar 22;24:100876. doi: 10.1016/j.eucr.2019.100876. eCollection 2019 May.
2
Laparoscopic bilateral cortical-sparing adrenalectomy for pheochromocytoma.腹腔镜双侧保留皮质肾上腺切除术治疗嗜铬细胞瘤
Surg Endosc. 2016 Dec;30(12):5622-5623. doi: 10.1007/s00464-016-4919-5. Epub 2016 May 13.
3
Management of pheochromocytomas in patients with multiple endocrine neoplasia type 2 syndromes.2型多发性内分泌腺瘤综合征患者嗜铬细胞瘤的管理。
Ann Surg. 1993 Jun;217(6):595-601; discussion 601-3. doi: 10.1097/00000658-199306000-00001.
4
Massive Biochemically Silent Pheochromocytoma Masquerading as Nonfunctioning Adrenocortical Cancer.伪装成无功能肾上腺皮质癌的巨大生化隐匿性嗜铬细胞瘤
JCEM Case Rep. 2023 Jun 7;1(3):luad061. doi: 10.1210/jcemcr/luad061. eCollection 2023 May.
5
Surgical management of hereditary pheochromocytoma.遗传性嗜铬细胞瘤的外科治疗
J Am Coll Surg. 2004 Apr;198(4):525-34; discussion 534-5. doi: 10.1016/j.jamcollsurg.2003.12.001.
6
Estimated risk of pheochromocytoma recurrence after adrenal-sparing surgery in patients with multiple endocrine neoplasia type 2A.2A 型多发性内分泌腺瘤病患者行肾上腺保留手术后嗜铬细胞瘤复发的估计风险。
Arch Surg. 2006 Dec;141(12):1199-205; discussion 1205. doi: 10.1001/archsurg.141.12.1199.
7
Pre- and peri-operative characteristics, complications and outcomes of patients with biochemically silent pheochromocytomas; a case series.生化无症状型嗜铬细胞瘤患者的围手术期特征、并发症及结局:病例系列。
Endocrine. 2022 Dec;78(3):570-579. doi: 10.1007/s12020-022-03182-w. Epub 2022 Sep 8.
8
Multiple endocrine neoplasia 2A (MEN 2A) syndrome.多发性内分泌腺瘤病2A(MEN 2A)综合征。
Bratisl Lek Listy. 2018;119(2):120-125. doi: 10.4149/BLL_2018_034.
9
Anesthetic Management of Clinically Silent Familial Pheochromocytoma with MEN 2A: A Report of Four Cases.伴有2A型多发性内分泌腺瘤病的临床无症状性家族性嗜铬细胞瘤的麻醉管理:4例报告
Indian J Surg. 2016 Oct;78(5):414-417. doi: 10.1007/s12262-016-1539-1. Epub 2016 Aug 15.
10
Adrenalectomy for familial pheochromocytoma in the laparoscopic era.腹腔镜时代家族性嗜铬细胞瘤的肾上腺切除术
Ann Surg. 2002 May;235(5):713-20; discussion 720-1. doi: 10.1097/00000658-200205000-00014.

引用本文的文献

1
Hypertensive Urgencies Following Percutaneous Adrenal Mass Biopsy in a Day Surgery Unit: A Case Report.日间手术单元经皮肾上腺肿块活检术后的高血压急症:一例报告
Cureus. 2025 Mar 14;17(3):e80568. doi: 10.7759/cureus.80568. eCollection 2025 Mar.
2
Silent pheochromocytoma in adrenal incidentaloma: unveiling clinical and radiological characteristics.肾上腺偶发瘤中的无症状嗜铬细胞瘤:揭示临床和放射学特征
Ann Surg Treat Res. 2024 Jan;106(1):38-44. doi: 10.4174/astr.2024.106.1.38. Epub 2023 Dec 28.
3
Pheochromocytoma: a changing perspective and current concepts.

本文引用的文献

1
Preoperative alpha-blockade in phaeochromocytoma and paraganglioma: is it always necessary?嗜铬细胞瘤和副神经节瘤的术前α-受体阻滞剂治疗:是否总是必要?
Clin Endocrinol (Oxf). 2017 Mar;86(3):309-314. doi: 10.1111/cen.13284. Epub 2016 Dec 15.
2
Bilateral adrenal masses: a single-centre experience.双侧肾上腺肿块:单中心经验。
Endocr Connect. 2016 Mar;5(2):92-100. doi: 10.1530/EC-16-0015. Epub 2016 Apr 1.
3
Preoperative management of the pheochromocytoma patient.嗜铬细胞瘤患者的术前管理。
嗜铬细胞瘤:不断变化的观点与当前概念
Ther Adv Endocrinol Metab. 2023 Oct 29;14:20420188231207544. doi: 10.1177/20420188231207544. eCollection 2023.
4
Robotic Adrenalectomy in a Patient With Neurofibromatosis Type 1 and Pheochromocytoma.1型神经纤维瘤病合并嗜铬细胞瘤患者的机器人肾上腺切除术
Cureus. 2023 Apr 4;15(4):e37097. doi: 10.7759/cureus.37097. eCollection 2023 Apr.
5
Silent pheochromocytoma and paraganglioma: Systematic review and proposed definitions for standardized terminology.无症状嗜铬细胞瘤和副神经节瘤:系统评价和标准化术语建议定义。
Front Endocrinol (Lausanne). 2022 Oct 17;13:1021420. doi: 10.3389/fendo.2022.1021420. eCollection 2022.
6
Pre- and peri-operative characteristics, complications and outcomes of patients with biochemically silent pheochromocytomas; a case series.生化无症状型嗜铬细胞瘤患者的围手术期特征、并发症及结局:病例系列。
Endocrine. 2022 Dec;78(3):570-579. doi: 10.1007/s12020-022-03182-w. Epub 2022 Sep 8.
7
Personalized Management of Pheochromocytoma and Paraganglioma.《嗜铬细胞瘤和副神经节瘤的个体化管理》
Endocr Rev. 2022 Mar 9;43(2):199-239. doi: 10.1210/endrev/bnab019.
8
Preoperative Management of Pheochromocytoma and Paraganglioma.《嗜铬细胞瘤和副神经节瘤的术前管理》。
Front Endocrinol (Lausanne). 2020 Sep 29;11:586795. doi: 10.3389/fendo.2020.586795. eCollection 2020.
9
A case of an unexpected posterior mediastinal functional paraganglioma: case report and literature review.一例意外的后纵隔功能性副神经节瘤:病例报告及文献复习。
BMC Anesthesiol. 2020 May 8;20(1):109. doi: 10.1186/s12871-020-01026-6.
J Clin Endocrinol Metab. 2007 Nov;92(11):4069-79. doi: 10.1210/jc.2007-1720.
4
Pheochromocytomas and secreting paragangliomas.嗜铬细胞瘤与分泌型副神经节瘤。
Orphanet J Rare Dis. 2006 Dec 8;1:49. doi: 10.1186/1750-1172-1-49.
5
Incidentally discovered adrenal masses.偶然发现的肾上腺肿块。
Endocr Rev. 1995 Aug;16(4):460-84. doi: 10.1210/edrv-16-4-460.