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FBXW2 suppresses proliferation and invasion of lung cancer cells by targeting SKP2 and β-catenin.
Mol Cell Oncol. 2019 May 8;6(4):1607458. doi: 10.1080/23723556.2019.1607458. eCollection 2019.
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USP2 is an SKP2 deubiquitylase that stabilizes both SKP2 and its substrates.
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FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis.
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E3 Ligase FBXW2 Is a New Therapeutic Target in Obesity and Atherosclerosis.
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Regulation of neddylation and deneddylation of cullin1 in SCFSkp2 ubiquitin ligase by F-box protein and substrate.
Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11515-20. doi: 10.1073/pnas.0603921103. Epub 2006 Jul 21.
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The FBXW2-MSX2-SOX2 axis regulates stem cell property and drug resistance of cancer cells.
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Pan-cancer analysis of FBXW family with potential implications in prognosis and immune infiltration.
Front Immunol. 2022 Dec 14;13:1084339. doi: 10.3389/fimmu.2022.1084339. eCollection 2022.
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Ubiquitination of NF-κB p65 by FBXW2 suppresses breast cancer stemness, tumorigenesis, and paclitaxel resistance.
Cell Death Differ. 2022 Feb;29(2):381-392. doi: 10.1038/s41418-021-00862-4. Epub 2021 Aug 31.
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The Role of Cullin-RING Ligases in Striated Muscle Development, Function, and Disease.
Int J Mol Sci. 2020 Oct 26;21(21):7936. doi: 10.3390/ijms21217936.
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F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects.
Theranostics. 2020 Mar 4;10(9):4150-4167. doi: 10.7150/thno.42735. eCollection 2020.

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
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Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities.
Cell. 2017 Jun 1;169(6):985-999. doi: 10.1016/j.cell.2017.05.016.
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F-box protein interactions with the hallmark pathways in cancer.
Semin Cancer Biol. 2016 Feb;36:3-17. doi: 10.1016/j.semcancer.2015.09.013. Epub 2015 Sep 28.
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SCF ubiquitin ligase-targeted therapies.
Nat Rev Drug Discov. 2014 Dec;13(12):889-903. doi: 10.1038/nrd4432. Epub 2014 Nov 14.
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Roles of F-box proteins in cancer.
Nat Rev Cancer. 2014 Apr;14(4):233-47. doi: 10.1038/nrc3700.
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The β-catenin destruction complex.
Cold Spring Harb Perspect Biol. 2013 Jan 1;5(1):a007898. doi: 10.1101/cshperspect.a007898.
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Mechanism of hypoxia-induced GCM1 degradation: implications for the pathogenesis of preeclampsia.
J Biol Chem. 2009 Jun 26;284(26):17411-9. doi: 10.1074/jbc.M109.016170. Epub 2009 May 5.
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Systematic analysis and nomenclature of mammalian F-box proteins.
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