Mizutani Kenichi, Mukai Munenori, Nagatsuka Hitoshi, Yamada Sohsuke
Department of Pathology and Laboratory Medicine, Kanazawa Medical University, Kahoku, Japan.
Department of Pathology, Kouseiren Takaoka Hospital, Takaoka, Japan.
Clin Pathol. 2019 Feb 21;12:2632010X19831257. doi: 10.1177/2632010X19831257. eCollection 2019 Jan-Dec.
Congenital granular cell epulis is a rare and benign lesion in newborn. There are some papers of the entity; however, there are very few reports focusing on its macroscopic view.
A 0-day-old boy was noted to have a mass consisting of multiple nodules on maxillary gingiva, and it was excised. The mass was measured about 2 cm in its greatest diameter. Surface of cross-section was characteristically whitish-yellow and very smooth. Histopathologically, the lesion was composed of a proliferation of large polygonal cells with demarcated cell membrane, granular cytoplasm, and small uniform nuclei. Immunohistochemically, these cells were negative for S100. The diagnosis was concluded as congenital granular cell epulis.
We reported a typical case of congenital granular cell epulis. It is noteworthy that the cross-section observed in this case was very characteristically whitish-yellow and smooth.