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血管靶向光动力疗法开启前列腺癌“超级主动监测”时代。

Prostate cancer "super-active surveillance" era opened by vascular targeted photodynamic therapy.

作者信息

Corradi Renato B, Travassos Thiago C, Reis Leonardo O

机构信息

UroScience, Pontifical Catholic University of Campinas, Campinas, SP, Brazil.

University of Campinas, Campinas, SP, Brazil.

出版信息

Res Rep Urol. 2019 May 29;11:157-163. doi: 10.2147/RRU.S178038. eCollection 2019.

DOI:10.2147/RRU.S178038
PMID:31214532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6549684/
Abstract

The "super-active surveillance" concept denotes any active surveillance optimization that allows longer surveillance periods, with the main intention of avoiding overtreatment, by safely eliminating or postponing radical treatment. Super-active surveillance might add to the oncological control with minimal functional impact and similar quality of life compared to active surveillance, which has proved to be safe in well-selected patients. Vascular targeted photodynamic therapy has pioneering shown to significantly reduce the upgrade on subsequent biopsies, resulting in fewer cases converted to radical therapy, and any energy source can be applied to the super-active surveillance concept allowing more men to consider a tissue-preserving therapy for prostate cancer.

摘要

“超级主动监测”概念指的是任何能延长监测期的主动监测优化措施,其主要目的是通过安全地消除或推迟根治性治疗来避免过度治疗。与主动监测相比,超级主动监测可能在对功能影响最小且生活质量相似的情况下增强肿瘤学控制,主动监测在精心挑选的患者中已被证明是安全的。血管靶向光动力疗法已率先证明能显著减少后续活检中的升级情况,从而减少转为根治性治疗的病例,并且任何能量源都可应用于超级主动监测概念,使更多男性能够考虑采用保留组织疗法治疗前列腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c24/6549684/f4129ea369df/RRU-11-157-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c24/6549684/f4129ea369df/RRU-11-157-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c24/6549684/f4129ea369df/RRU-11-157-g0001.jpg

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Ablation energies for focal treatment of prostate cancer.前列腺癌病灶治疗的消融能量。
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