Department of Endocrinology, Copenhagen University Hospital of Hvidovre, Kettegaards Allé 30, DK-2650, Hvidovre, Denmark.
Head of Department, Department of Orthopedics, Copenhagen University Hospital of Bispebjerg, Bispebjerg Bakke 23, DK-2400, Copenhagen NV, Denmark.
Arch Osteoporos. 2019 Jun 19;14(1):63. doi: 10.1007/s11657-019-0612-3.
Opportunities to evaluate, treat, and prevent future osteoporotic fractures are often being overlooked, especially in patients with a prior osteoporotic fracture. We find that an intensive outreach osteoporosis investigation strategy can help increase the number of patients investigated and treated for osteoporosis following a hip fracture.
Patients experiencing a hip fracture are subject to an increased risk of subsequent fractures. This suggests an urgent need to develop strategies that will allow a higher number of patients with fragility hip fractures to be investigated and treated for osteoporosis. In accordance, we developed a secondary osteoporosis prevention program and evaluated the results of the program.
In the study period, 1071 patients with a hip fracture were admitted to Hvidovre University Hospital. Eligible patients were offered an osteoporosis investigation program, which included a DXA-scan with vertebral fracture assessment and a medical consultation. The data retrieved from this program were registered and analyzed. The primary goal of the study was to describe the number of subjects, who completed the program, and to characterize the initiated osteoporosis treatment. Secondary outcomes evaluated were prevalence of DXA-verified osteoporosis, changes in T-score due to treatment, and 1-year mortality rate.
In total, 557 patients were offered participation of which 333 patients completed the full program. Among these, 159 patients had DXA-verified osteoporosis and 192 patients were started treatment. This resulted in a significant higher T-score at the lumbar spine and femoral neck compared with subjects not treated. Additionally, we report a 1-year mortality rate of 27.7% among all patients with hip fracture.
We report that an intensive outreach osteoporosis investigation program can help increase the number of hip fracture patients being tested and treated for osteoporosis. Further, the initiation of treatment can significantly increase the T-score.
髋部骨折患者存在再次骨折的风险增加。这表明迫切需要制定策略,以便对更多脆性髋部骨折患者进行骨质疏松症的调查和治疗。为此,我们制定了二级骨质疏松预防计划,并评估了该计划的结果。
在研究期间,1071 名髋部骨折患者入住 Hvidovre 大学医院。符合条件的患者可选择参加骨质疏松症调查计划,该计划包括 DXA 扫描(包括椎体骨折评估)和医疗咨询。从该计划中获取的数据进行了登记和分析。该研究的主要目标是描述完成该计划的患者人数,并描述开始的骨质疏松症治疗情况。次要结局评估包括 DXA 确诊骨质疏松症的患病率、治疗后 T 评分的变化以及 1 年死亡率。
共邀请了 557 名患者参加,其中 333 名患者完成了全部计划。在这些患者中,159 名患者经 DXA 确诊患有骨质疏松症,192 名患者开始接受治疗。与未接受治疗的患者相比,这些患者的腰椎和股骨颈的 T 评分显著更高。此外,我们报告所有髋部骨折患者的 1 年死亡率为 27.7%。
我们报告说,强化的骨质疏松症调查计划有助于增加髋部骨折患者接受骨质疏松症检测和治疗的人数。此外,治疗的启动可以显著提高 T 评分。