Beyls Christophe, Huette Pierre, Guilbart Mathieu, Nzonzuma Alphonse, Abou Arab Osama, Mahjoub Yazine
Department of Anesthesiology and Critical Care Medicine, Amiens University Medical Center, Amiens, France.
Département d'Anesthésie-Réanimation, CHU d'Amiens Picardie, Amiens, France.
Perfusion. 2020 Jan;35(1):82-85. doi: 10.1177/0267659119853949. Epub 2019 Jun 20.
The objective of the study is to describe an emergency procedure for left ventricle venting during veno-arterial extracorporeal life support for refractory cardiac arrest. Veno-arterial extracorporeal membrane oxygenation is widely used in refractory cardiac arrest but is characterized by an increase in left ventricle afterload, which may impair cardiac contractility improvement. Different left ventricle venting techniques are available. We report the use of a surgical approach with sternotomy for left ventricle venting in a 21-year-old patient who was placed under veno-arterial extracorporeal membrane oxygenation for refractory cardiac arrest with severe pulmonary edema, respiratory failure, and left ventricle stasis. A 21-year-old woman was admitted for laparoscopic sleeve gastrectomy. In the recovery room, she developed a refractory circulatory shock. Transthoracic echocardiography revealed a dilated cardiomyopathy with severe left ventricle systolic dysfunction (left ventricle ejection fraction at 20%). Coronary angiogram was normal. On day 2, she underwent laparotomy for sepsis and she presented cardiac arrest secondary to ventricular tachycardia. We proceeded to peripheral veno-arterial extracorporeal membrane oxygenation as the cardiac arrest was refractory. A miniaturized veno-arterial extracorporeal membrane oxygenation system was implanted into the right femoral vessels onsite .The low flow duration was 40 minutes. Veno-arterial extracorporeal membrane oxygenation blood flow was set to 3 L min, resulting in a closed aortic valve and a massive pulmonary edema. Transesophageal echocardiography showed left ventricular ejection fraction at 5% without aortic valve opening. We first implanted an intra-aortic balloon pump without clinical improvement. Transesophageal echocardiography revealed massive thrombus formation into the aortic root. We decided to perform an open surgical approach for left ventricle unload using a transmitral cannula (22 Fr) via the right superior pulmonary vein connected to the inflow tube of the veno-arterial extracorporeal membrane oxygenation with Y connection. Transesophageal echocardiography showed a full opening of aortic valve and elimination of valve aortic thrombus. Chest radiography showed a significant decrease of pulmonary congestion. We were able to withdraw extracorporeal life support organization on day 10 and discharged on day 54. Clinical explorations reveal a fulminant rocuronium-related hypersensitivity myocarditis. This salvage surgical technique using a modified central veno-arterial extracorporeal membrane oxygenation cannulation technique has efficiently decreased blood stasis and permitted rapid recovery.
本研究的目的是描述一种在难治性心脏骤停的静脉 - 动脉体外生命支持期间进行左心室排气的紧急程序。静脉 - 动脉体外膜肺氧合在难治性心脏骤停中被广泛应用,但其特点是左心室后负荷增加,这可能会损害心脏收缩力的改善。有多种不同的左心室排气技术。我们报告了一名21岁患者的情况,该患者因难治性心脏骤停伴严重肺水肿、呼吸衰竭和左心室淤血而接受静脉 - 动脉体外膜肺氧合,我们采用胸骨切开术的手术方法进行左心室排气。一名21岁女性因腹腔镜袖状胃切除术入院。在恢复室,她出现了难治性循环休克。经胸超声心动图显示扩张型心肌病伴严重左心室收缩功能障碍(左心室射血分数为20%)。冠状动脉造影正常。在第2天,她因脓毒症接受剖腹手术,随后因室性心动过速出现心脏骤停。由于心脏骤停难治,我们进行了外周静脉 - 动脉体外膜肺氧合。在现场将一个小型化的静脉 - 动脉体外膜肺氧合系统植入右股血管。低流量持续时间为40分钟。静脉 - 动脉体外膜肺氧合血流量设定为3L/min,导致主动脉瓣关闭和大量肺水肿。经食管超声心动图显示左心室射血分数为5%,主动脉瓣未开放。我们首先植入了主动脉内球囊泵,但临床症状未改善。经食管超声心动图显示主动脉根部形成大量血栓。我们决定采用开放手术方法,通过经右上肺静脉使用22Fr的二尖瓣插管进行左心室卸载,该插管通过Y形连接与静脉 - 动脉体外膜肺氧合的流入管相连。经食管超声心动图显示主动脉瓣完全开放,主动脉瓣血栓消除。胸部X线显示肺淤血明显减轻。我们在第10天能够撤除体外生命支持机构,并在第54天出院。临床检查发现为暴发性罗库溴铵相关的过敏性心肌炎。这种采用改良的中心静脉 - 动脉体外膜肺氧合插管技术的挽救性手术技术有效地减少了血液淤滞,并实现了快速康复。