Minter-Goedbloed E, Minter D M
Laboratório Central Conçalo Moniz, FUSEB, Bahia, Brazil.
Parasitol Res. 1987;73(6):565-7. doi: 10.1007/BF00535334.
A direct correlation was shown between bloodmeal intake in xenodiagnosis and subsequent infection rate with Trypanosoma (S.) cruzi, in first-stage nymphs of Panstrongylus megistus Burmeister. The parasitaemia of different hosts, or of the same host at intervals, thus can be compared indirectly by the proportion of first-stage nymphs infected in xenodiagnosis, if uniform distribution and infectivity of bloodstream trypomastigotes is assumed. This indirect comparison of host parasitaemia provides important information not obtainable otherwise, since parasitaemia often is too low for quantitative measurement. Infection rates were compared of first-instar P. megistus in experimental xenodiagnosis of patients and animals. All T. cruzi stocks originated from an endemic area of Brazil (Bahia state). Several batches of nymphs were fed sequentially on some hosts, to assess fluctuations of parasitaemia with time; in others, particularly the patients, xenodiagnosis was carried out only once.
在大锥猎蝽（Panstrongylus megistus Burmeister）的第一龄若虫中，异种诊断中的血餐摄入量与随后感染克氏锥虫（Trypanosoma (S.) cruzi）的感染率之间呈现直接相关性。如果假定血液中的锥鞭毛体分布均匀且具有感染性，那么不同宿主或同一宿主在不同时间间隔的寄生虫血症就可以通过异种诊断中感染的第一龄若虫的比例进行间接比较。宿主寄生虫血症的这种间接比较提供了通过其他方式无法获得的重要信息，因为寄生虫血症通常过低，无法进行定量测量。比较了在患者和动物的实验性异种诊断中第一龄大锥猎蝽的感染率。所有克氏锥虫菌株均源自巴西的一个流行地区（巴伊亚州）。几批若虫依次叮咬一些宿主，以评估寄生虫血症随时间的波动；在其他宿主中，特别是患者，只进行了一次异种诊断。
