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肢体和躯干部Ⅱ型动静脉畸形的乙醇栓塞术分类和治疗结果。

Subclassification and Treatment Results of Ethanol Embolotherapy of Type II Arteriovenous Malformations of the Extremity and Body.

机构信息

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-Gu, Seoul 06351, Korea.

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-Gu, Seoul 06351, Korea.

出版信息

J Vasc Interv Radiol. 2019 Sep;30(9):1443-1451. doi: 10.1016/j.jvir.2019.03.007. Epub 2019 Jun 20.

Abstract

PURPOSE

To evaluate the safety and efficacy of ethanol and coil embolization of type II arteriovenous malformation (AVM) according to a new subtype classification.

MATERIALS AND METHODS

Eighty-four type II AVMs in the body or extremity of 79 patients who underwent AVM treatment from 1996 to 2017 were retrospectively subclassified according to the angiographic morphology of the draining vein as type IIa (arterioles shunt to focal segment of single draining vein), type IIb (arterioles shunt to venous sac with multiple draining veins), and type IIc (arterioles shunt along long segment of draining vein). Coil and ethanol embolization of the focal or long segment of the draining vein or the venous sac was performed with direct puncture or transvenous approach according to subtype. Treatment outcomes, number of treatment sessions, and complications were analyzed.

RESULTS

AVM cure (ie, complete embolization) rates were 95%, 76%, and 65% in types IIa, IIb, and IIc AVMs, respectively. The cure rate of type IIa AVMs was significantly better than that of type IIc AVMs (P = .015). Median numbers of treatment sessions were 1 in types IIa and IIb AVMs and 2.5 in type IIc AVMs, with a significant difference between type IIc and the other 2 types (P < .05). Minor complications occurred in 20% of patents and major complications occurred in 7%.

CONCLUSIONS

The cure rate of type IIa AVMs was significantly better than that of type IIc AVMs, which also required significantly more treatment sessions than the other 2 types.

摘要

目的

根据一种新的亚型分类,评估乙醇和线圈栓塞治疗 II 型动静脉畸形(AVM)的安全性和有效性。

材料与方法

回顾性分析 1996 年至 2017 年期间接受 AVM 治疗的 79 例患者 84 个位于身体或四肢的 II 型 AVM,根据引流静脉的血管造影形态将其分为 IIa 型(小动脉分流至单一引流静脉的局灶段)、IIb 型(小动脉分流至具有多个引流静脉的静脉囊中)和 IIc 型(小动脉沿引流静脉的长段分流)。根据亚型,采用直接穿刺或经静脉途径对引流静脉的局灶或长段或静脉囊进行线圈和乙醇栓塞。分析治疗结果、治疗次数和并发症。

结果

IIa、IIb 和 IIc 型 AVM 的 AVM 治愈率(即完全栓塞)分别为 95%、76%和 65%。IIa 型 AVM 的治愈率明显优于 IIc 型 AVM(P =.015)。IIa 和 IIb 型 AVM 的治疗次数中位数均为 1 次,而 IIc 型 AVM 为 2.5 次,IIc 型与其他 2 型之间存在显著差异(P <.05)。20%的患者发生轻微并发症,7%的患者发生严重并发症。

结论

IIa 型 AVM 的治愈率明显优于 IIc 型 AVM,后者所需的治疗次数也明显多于其他 2 种类型。

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