Department of Electrical Engineering, Indian Institute of Technology Hyderabad, 502285, India.
School of Medicine, University of California Davis, USA.
Biosens Bioelectron. 2019 Sep 15;141:111441. doi: 10.1016/j.bios.2019.111441. Epub 2019 Jun 16.
Atrazine, a class 3a carcinogen, is a pesticide of chloro triazine family and is known to severely affect the human endocrine system upon consumption. The toxic effects of atrazine cause damage not only to the humans but also to animals and plants. In lieu of the detrimental effects of atrazine on environment, it is essential to develop a sensor platform capable of its detection in water. Here, we propose ultrasensitive electrochemical detection of atrazine using electrospun SnO nanofibers. In this study, the nanofibers have been characterized using Field Emission Spectroscopy, X-ray diffraction analysis (XRD), X-ray photoelectron spectroscopy (XPS), UV-Vis-NIR spectroscopy and Fourier transform infrared spectroscopy (FTIR). Using a label-free transduction, we have detected atrazine in fairly low concentrations, with the limit of detection being 0.9 zM and the sensitivity being 4.11 (μA/μM)/cm, in a wide dynamic detection range varying from 1 zM to 1 μM. Furthermore, we have reported atrazine detection in trace levels in spiked real time water samples, which is an essential step in ensuring that the sensing platform can be deployed for practical applications. In addition to this, the sensor exhibits excellent selectivity, reasonable stability (when stored at 4 °C), and good interference-resistance.
莠去津，一种 3a 类致癌物质，是三氯乙嗪类农药，已知在摄入后会严重影响人体内分泌系统。莠去津的毒性不仅对人类，而且对动植物都会造成损害。鉴于莠去津对环境的有害影响，开发一种能够在水中检测其的传感器平台至关重要。在这里，我们提出使用电纺 SnO 纳米纤维对莠去津进行超灵敏电化学检测。在这项研究中，使用场发射光谱、X 射线衍射分析（XRD）、X 射线光电子能谱（XPS）、紫外可见近红外光谱和傅里叶变换红外光谱（FTIR）对纳米纤维进行了表征。我们使用无标记转导技术，以相当低的浓度检测到莠去津，检测限为 0.9zM，灵敏度为 4.11（μA/μM）/cm，在从 1zM 到 1μM 的宽动态检测范围内具有良好的检测性能。此外，我们还报告了在加标实时水样中痕量莠去津的检测，这是确保传感平台能够用于实际应用的重要步骤。除此之外，该传感器还表现出优异的选择性、合理的稳定性（在 4°C 下储存时）和良好的抗干扰性。
