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机器人手术与腹腔镜选择性结肠切除术治疗左侧憩室炎:基于国家外科质量改进计划(NSQIP)数据库的倾向评分匹配分析

Robotic versus laparoscopic elective colectomy for left side diverticulitis: a propensity score-matched analysis of the NSQIP database.

作者信息

Al-Temimi Mohammed H, Chandrasekaran Bindupriya, Agapian Johan, Peters Walter R, Wells Katrina O

机构信息

Department of Surgery, Division of Colorectal Surgery, Baylor University Medical Center, 3409 Worth St# 640, Dallas, TX, 75246, USA.

Department of Surgery, Kaiser Permanente Fontana Medical Center, 9961 Sierra Ave., Fontana, CA, 92335, USA.

出版信息

Int J Colorectal Dis. 2019 Aug;34(8):1385-1392. doi: 10.1007/s00384-019-03334-x. Epub 2019 Jun 23.

Abstract

PURPOSE

Robotic surgery might have an advantage over conventional laparoscopy for colonic diverticulitis. We intend to compare both approaches in the elective management of left side diverticulitis.

METHODS

The National Surgical Quality Improvement Program (NSQIP) database (2012-2014) was surveyed for patients undergoing elective left/sigmoid colectomy for diverticulitis. Patient demographics, co-morbidities, disease complexity, and intraoperative details were matched on propensity scores derived from logistic regression model.

RESULTS

We identified 441 robotic and 6584 laparoscopic cases. Mean age was 56.8 years. Mean BMI was 29.5, and 46.5% of patients were males. Low preoperative albumin (< 3.5 mg/dl, 11.1% vs. 6.8%, p = 0.003), splenectomy (0.45% vs. 0.05%, p = 0.002), and enterotomy repair (1.1% vs. 0.4%, p = 0.029) were higher in the robotic group than the laparoscopic group. Hand assistance (35.8% vs. 42.9%, p = 0.003), splenic flexure takedown (41.5% vs. 49.2%, p = 0.002), and ureteric stent placement (18.6% vs. 23.5%, p = 0.017) were less common in the robotic group than the laparoscopic group. Case-matched analysis showed that robotic surgery was associated with shorter hospital stay (3.89 ± 2.18 days vs. 4.75 ± 3.25 days, p < 0.001), lower conversion rate (7.5% vs. 14.3%, p = 0.001), and longer operative time (219.2 ± 95.6 min vs. 188.8 ± 82.3 min, p < 0.001) than laparoscopic surgery. Robotic approach was associated with lower overall morbidity in multivariate analysis (OR = 0.72, 95% CI = 0.55-0.96), but not in case-matched analysis (14.4% vs. 19.2%, p = 0.058).

CONCLUSIONS

Robotic surgery is associated with shorter hospital stay and lower conversion rate and may offer lower overall morbidity than laparoscopy after elective left side colectomy for diverticulitis. Controlled prospective studies are needed to confirm these findings.

摘要

目的

机器人手术在结肠憩室炎治疗方面可能优于传统腹腔镜手术。我们旨在比较这两种方法在左侧憩室炎择期治疗中的效果。

方法

对国家外科质量改进计划(NSQIP)数据库(2012 - 2014年)进行调查,选取因憩室炎接受择期左半结肠/乙状结肠切除术的患者。根据逻辑回归模型得出的倾向得分,对患者的人口统计学特征、合并症、疾病复杂性及术中细节进行匹配。

结果

我们识别出441例机器人手术病例和6584例腹腔镜手术病例。平均年龄为56.8岁。平均体重指数为29.5,46.5%的患者为男性。机器人手术组术前白蛋白水平低(<3.5mg/dl,11.1%对6.8%,p = 0.003)、脾切除术(0.45%对0.05%,p = 0.002)和肠切开修复术(1.1%对0.4%,p = 0.029)的发生率高于腹腔镜手术组。机器人手术组手辅助操作(35.8%对42.9%,p = 0.003)、脾曲游离(41.5%对49.2%,p = 0.002)和输尿管支架置入(18.6%对23.5%,p = 0.017)的发生率低于腹腔镜手术组。病例匹配分析显示,与腹腔镜手术相比,机器人手术住院时间更短(3.89±2.18天对4.75±3.25天,p<0.001)、中转率更低(7.5%对14.3%,p = 0.001),但手术时间更长(219.2±95.6分钟对188.8±82.3分钟,p<0.001)。在多变量分析中,机器人手术方法与总体发病率较低相关(OR = 0.72,95%CI = 0.55 - 0.96),但在病例匹配分析中并非如此(14.4%对19.2%,p = 0.058)。

结论

机器人手术与较短的住院时间和较低的中转率相关,在左侧结肠憩室炎择期切除术后,其总体发病率可能低于腹腔镜手术。需要进行对照前瞻性研究来证实这些发现。

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