Munno I, Pellegrino N M, Fumo G, Barbieri G, Polimeno G, de Filippis V, Jirillo E
Istituto di Microbiologia Medica, Università di Bari, Policlinico, Italy.
Cytobios. 1987;52(210-211):167-73.
Twenty three patients with lepromatous leprosy (LL) not in reactional phase and bacteriologically negative were evaluated for their immune status (T cell frequency and interferon gamma production). In six patients with deficits of both immune parameters, a synthetic thymic extract (TP-5) was administered. At the end of the treatment, a full recovery of immune dysfunction was observed. In the light of these results, the efficacy of TP-5 as an immunomodulating agent in LL patients is discussed.
对23例非反应期且细菌学检查阴性的瘤型麻风（LL）患者进行了免疫状态（T细胞频率和γ干扰素产生）评估。在6例免疫参数均有缺陷的患者中，给予了一种合成胸腺提取物（TP - 5）。治疗结束时，观察到免疫功能障碍完全恢复。根据这些结果，讨论了TP - 5作为LL患者免疫调节剂的疗效。
