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[阿尔茨海默型老年痴呆症的脑电图变化]

[EEG changes in senile dementia of the Alzheimer type].

作者信息

Logar C, Grabmair W, Schneider G, Lechner H

机构信息

Psychiatrisch-Neurologische Universitätsklinik Graz.

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1987 Dec;18(4):214-7.

PMID:3123199
Abstract

Character and extent of changes in EEG in 45 patients with senile dementia of Alzheimer type (SDAT) were reported and the EEG-findings of patients with moderate (18) or severe (27) dementia were compared. The EEG-findings in these patients were compared with a group of 82 patients with multi-infarct dementia (MID). The EEG showed pathological results in 37 patients with predominating general changes (59%). In patients with severe dementia significantly more pathological results especially a significantly slower basic rhythm could be found. The degree of the cerebral atrophy verified by CT did not correspond with character and extent of the changes in EEG. The comparison between patients with SDAT and 82 patients with MID, revealed a significantly more frequent occurrence of unilateral slowing of the basic rhythm but a less frequent occurrence of focal changes. However, there was no significant difference in the number of normal and pathological EEG. The comparison between patients with SDAT and patients with MID without neurological deficit failed to show a significant difference in the number of normal and pathological EEG as well. It could be shown that in patients with severe dementia the EEG revealed significantly more pathological results as well as a significantly slower basic rhythm. However, the EEG could not differentiate between SDAT and MID.

摘要

报告了45例阿尔茨海默型老年痴呆(SDAT)患者脑电图(EEG)变化的特征及程度,并对中度(18例)或重度(27例)痴呆患者的EEG结果进行了比较。将这些患者的EEG结果与一组82例多发梗死性痴呆(MID)患者进行了比较。EEG显示37例患者有以普遍性改变为主的病理结果(59%)。在重度痴呆患者中可发现更多的病理结果,尤其是基础节律明显减慢。经CT证实的脑萎缩程度与EEG变化的特征及程度不相符。SDAT患者与82例MID患者的比较显示,基础节律单侧减慢的发生率明显更高,但局灶性改变的发生率较低。然而,正常EEG和异常EEG的数量没有显著差异。SDAT患者与无神经功能缺损的MID患者的比较也未显示正常EEG和异常EEG的数量有显著差异。结果表明,在重度痴呆患者中,EEG显示出明显更多的病理结果以及明显更慢的基础节律。然而,EEG无法区分SDAT和MID。

相似文献

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Computerized electroencephalography in the evaluation of early dementia.计算机化脑电图在早期痴呆评估中的应用
Brain Topogr. 1989 Summer;1(4):271-82. doi: 10.1007/BF01129605.