Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster, Corrensstraße 40, 48149, Münster, Germany.
Angew Chem Int Ed Engl. 2019 Sep 23;58(39):13654-13664. doi: 10.1002/anie.201906124. Epub 2019 Aug 8.
Strategies to achieve spatiotemporal regulation of pre-existing alkenes via external stimuli are essential given the ubiquity of feedstock olefins in chemistry and their downstream applications. Mirroring the 1-0 switch that underpins mammalian vision through selective geometric isomerisation in retinal, strategies to manipulate 2D space by both geometric and positional isomerisation of alkenes via chemical, thermal and light-driven processes are being intensively pursued. This minireview highlights the current state of the art in activating and achieving directionality in these fundamental chemical transformations.
鉴于化学原料烯烃在化学和下游应用中的普遍性，通过外部刺激实现预先存在的烯烃的时空调控的策略至关重要。通过视网膜中选择性几何异构化来模拟支撑哺乳动物视觉的 1-0 开关，通过化学、热和光驱动过程来操纵烯烃的几何和位置异构化以控制 2D 空间的策略正在被深入研究。这篇小综述强调了在这些基本化学转化中激活和实现方向性的最新技术状态。
