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西班牙坎塔布里亚自治区 2 型糖尿病患者血脂异常的流行情况及其相关危险因素。

The prevalence and risk factors associated with dyslipidemia in type 2 diabetic patients in the autonomous Region of Cantabria.

机构信息

Programa de Doctorado en Ciencias de la Salud, Universidad Católica San Antonio de Murcia, Murcia, España.

Cátedra de Riesgo Cardiovascular, Universidad Católica San Antonio de Murcia, Murcia, España.

出版信息

Endocrinol Diabetes Nutr (Engl Ed). 2020 Feb;67(2):102-112. doi: 10.1016/j.endinu.2019.04.010. Epub 2019 Jun 21.

Abstract

BACKGROUND AND OBJECTIVE

Dyslipidemia is one of the main risk factors in cardiovascular disease in patients with diabetes mellitus type 2 (DM2). The aim of this study is to evaluate the prevalence and risk factors associated with dyslipidemia in the population with diabetes mellitus type 2 in the region of Cantabria.

MATERIAL AND METHODS

This is a transversal study carried out at Cantabrian primary health care centres (n=680). A representative, random sample of the population with DM2, ranging from 18-85, was selected using a multistage procedure. The medical records were obtained, and by means of interviews the data of the risk factors to be studied was secured. The correlation with dyslipidemia was analysed by means of logistic regression.

RESULTS

There were 52.1% of males, the average age was 69.8, the evolution of diabetes was 9.99 years, 84.3% had arterial hypertension, 76.6% were overweight or obese and the average HbA1c was 6.96%. The prevalence of dyslipidemia was 85.3%, and in the bivariate analysis this is associated with a history of peripheral artery disease, controlled diabetes, antihypertensive treatment, glomerular filtration, HbA1c>7%, body fat estimated as being either overweight or obese, a history of cardiovascular disease, age and HbA1c. In the multivariate analysis the independent factors were being female and a history of cardiovascular disease.

CONCLUSION

The prevalence of dyslipidemia in our study was 85.3%, and is consistent with figures found in previous published studies. The independent associated risk factors were being female and a past medical history of cardiovascular disease.

摘要

背景和目的

血脂异常是 2 型糖尿病(DM2)患者心血管疾病的主要危险因素之一。本研究旨在评估坎塔布里亚地区 2 型糖尿病患者血脂异常的流行情况及相关危险因素。

材料和方法

这是在坎塔布里亚初级保健中心进行的横断面研究(n=680)。采用多阶段程序,选择了年龄在 18-85 岁之间的代表性随机 2 型糖尿病患者人群样本。通过病历获取和访谈获取研究相关危险因素的数据。通过逻辑回归分析与血脂异常的相关性。

结果

男性占 52.1%,平均年龄为 69.8 岁,糖尿病病程为 9.99 年,84.3%有动脉高血压,76.6%超重或肥胖,平均 HbA1c 为 6.96%。血脂异常的患病率为 85.3%,在单变量分析中,这与外周动脉疾病史、糖尿病控制、降压治疗、肾小球滤过率、HbA1c>7%、体脂肪超重或肥胖、心血管疾病史、年龄和 HbA1c 有关。多变量分析中独立的危险因素是女性和心血管疾病史。

结论

本研究中血脂异常的患病率为 85.3%,与先前发表的研究结果一致。独立相关的危险因素是女性和心血管疾病史。

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