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Adequacy of measurements in compartmental modelling of metabolic systems.

作者信息

Brown R F, Carson E R, Finkelstein L, Godfrey K R, Jones R P

出版信息

Med Biol Eng Comput. 1979 Mar;17(2):216-22. doi: 10.1007/BF02440932.

DOI:10.1007/BF02440932
PMID:312398
Abstract
摘要

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引用本文的文献

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Identifiable pharmacokinetic models: the role of extra inputs and measurements.可识别的药代动力学模型:额外输入和测量的作用。
J Pharmacokinet Biopharm. 1980 Dec;8(6):633-48. doi: 10.1007/BF01060058.
2
Evaluation of alternative model structures of metabolic systems: two case studies on model identification and validation.代谢系统替代模型结构的评估:模型识别与验证的两个案例研究
Med Biol Eng Comput. 1982 Jul;20(4):444-50. doi: 10.1007/BF02442404.
3
Uncertainties in compartmental analysis studied by linear programming techniques.通过线性规划技术研究的房室分析中的不确定性。

本文引用的文献

1
Determination of the circulating red cell volume in man by radioactive chromium.用放射性铬测定人体循环红细胞容量
J Clin Invest. 1950 Dec;29(12):1614-9. doi: 10.1172/JCI102404.
2
Studies of bilirubin kinetics in normal adults.正常成年人胆红素动力学研究。
J Clin Invest. 1969 Nov;48(11):2176-90. doi: 10.1172/JCI106184.
3
Regional variations in the proportion of red cells in the blood in man.人类血液中红细胞比例的区域差异。
Med Biol Eng Comput. 1986 Jan;24(1):97-9. doi: 10.1007/BF02441613.
Br J Haematol. 1969 Jun;16(6):557-71. doi: 10.1111/j.1365-2141.1969.tb00437.x.
4
Constitutional hepatic dysfunction (Gilbert's syndrome). A new definition based on kinetic studies with unconjugated radiobilirubin.体质性肝功能不全(吉尔伯特综合征)。基于非结合放射性胆红素动力学研究的新定义。
Am J Med. 1970 Sep;49(3):296-305. doi: 10.1016/s0002-9343(70)80020-1.
5
Tracer experiment design for unique identification of nonlinear physiological systems.用于非线性生理系统唯一识别的示踪剂实验设计。
Am J Physiol. 1976 Feb;230(2):476-85. doi: 10.1152/ajplegacy.1976.230.2.476.
6
Controllability, observability and structural identifiability of multi input and multi output biological compartmental systems.多输入多输出生物房室系统的可控性、可观测性和结构可识别性
IEEE Trans Biomed Eng. 1976 Mar;23(2):93-100. doi: 10.1109/tbme.1976.324568.
7
Modeling, identification and parameter estimation of bilirubin kinetics in normal, hemolytic and Gilbert's states.正常、溶血和吉尔伯特综合征状态下胆红素动力学的建模、识别与参数估计
Comput Biomed Res. 1975 Dec;8(6):522-37. doi: 10.1016/0010-4809(75)90024-5.
8
Comments on "controllability, observability and structural identifiability of multi input and multi output biological compartmental systems".
IEEE Trans Biomed Eng. 1977 Sep;24(5):495-6. doi: 10.1109/tbme.1977.326193.
9
Studies on the kinetics of unconjugated [14C]bilirubin metabolism in normal subjects and patients with compensated cirrhosis.正常受试者和代偿期肝硬化患者未结合[14C]胆红素代谢动力学研究。
Clin Sci Mol Med. 1977 Jun;52(6):555-70. doi: 10.1042/cs0520555.
10
Compartmental modelling based on methionine tolerance test data: a case study.基于蛋氨酸耐受性测试数据的房室模型:一个案例研究。
Med Biol Eng Comput. 1979 Mar;17(2):223-9. doi: 10.1007/BF02440933.