Protzel C, Hakenberg O W
Klinik für Urologie, Helios Kliniken Schwerin, Wismarsche Straße 393-397, 19055, Schwerin, Deutschland.
Klinik und Poliklinik für Urologie, Universitätsklinikum Rostock, Rostock, Deutschland.
Urologe A. 2019 Jul;58(7):774-780. doi: 10.1007/s00120-019-0973-7.
Due to its low incidence there is only very limited data concerning molecular markers in penile cancer. Recent studies show potential prognostic markers for lymph node metastasis, survival and response to chemotherapy or targeted therapy. Nevertheless the number of patients in the studies is very limited. Therefor clear recommendations for clinical decisions remain very weak. Patients with metastatic disease should be treated in clinical trials with translational biomarker research to improve the molecular tumor board in the future.
由于阴茎癌发病率较低，关于其分子标志物的数据非常有限。近期研究显示了淋巴结转移、生存率以及对化疗或靶向治疗反应的潜在预后标志物。然而，这些研究中的患者数量非常有限。因此，对于临床决策的明确建议仍然很薄弱。转移性疾病患者应在开展转化生物标志物研究的临床试验中接受治疗，以便未来改进分子肿瘤委员会。
