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股神经阻滞联合多模式关节周围浸润与股神经阻滞联合多模式关节周围浸润和关节内罗哌卡因硬膜外导管浸润对全膝关节置换术后镇痛效果的比较研究:一项前瞻性研究。

Comparative study of the influence of adductor canal block plus multimodal periarticular infiltration versus combined adductor canal block, multimodal periarticular infiltration and intra-articular epidural catheter ropivacaine infiltration on pain relief after total knee arthroplasty: a prospective study.

机构信息

Max Cure Hospital, Hyderabad, India.

出版信息

Musculoskelet Surg. 2020 Aug;104(2):201-206. doi: 10.1007/s12306-019-00613-2. Epub 2019 Jun 25.

DOI:10.1007/s12306-019-00613-2
PMID:31240665
Abstract

BACKGROUND

A combined regimen of adductor canal block (ACB) and multimodal periarticular infiltration (MPI) with local anesthetic (ropivacaine) is a known effective method of controlling pain in the first 6-8 h after total knee arthroplasty (TKA); however, managing breakthrough pain after their combined effect wears off can be challenging. We hypothesized that, by additionally leaving an intra-articular epidural catheter (IAEC) inside the knee with intermittent infiltration of local anesthetic in conjunction with ACB and MPI, it would help manage the breakthrough pain when their combined effect wears off.

METHODS

We did a prospective study in our institution between December 2015 and August 2016 on a total of 206 patients undergoing primary unilateral TKA. The initial consecutive 106 patients received ACB + MPI (Group 1, n = 106), and the subsequent 100 patients received ACB + MPI + IAEC (Group 2, n = 100). The primary outcome measure was pain using visual analogue scale (VAS) recorded at 6, 12, 24 and 48 h, and the secondary outcome measures were requirement for rescue analgesics and repeat adductor canal block and length of hospital stay.

RESULTS

There was no statistically significant difference in VAS scores between the two groups at 6 h but at 12, 24 and 48 h; there was a statistically significant difference between the two groups in terms of VAS scores, rescue analgesic requirements, repeat adductor canal block and shorter hospital stay favoring the ACB + MPI + IAEC group.

CONCLUSION

Intermittent knee infiltration with ropivacaine is a safe, reproducible and effective method to control pain in the first 48 h postoperative period after TKA.

摘要

背景

股神经阻滞(ACB)联合关节周围多模式浸润(MPI)加局部麻醉(罗哌卡因)是一种已知的有效方法,可以控制全膝关节置换术(TKA)后 6-8 小时内的疼痛;然而,当它们的联合作用消退后,管理突破性疼痛可能具有挑战性。我们假设,通过在膝关节内额外留置关节内硬膜外导管(IAEC),并结合 ACB 和 MPI 间歇性局部麻醉浸润,当它们的联合作用消退时,有助于管理突破性疼痛。

方法

我们在 2015 年 12 月至 2016 年 8 月在我们的机构进行了一项前瞻性研究,共纳入 206 例接受单侧初次 TKA 的患者。最初连续的 106 例患者接受 ACB+MPI(第 1 组,n=106),随后的 100 例患者接受 ACB+MPI+IAEC(第 2 组,n=100)。主要观察指标为术后 6、12、24 和 48 小时记录的视觉模拟评分(VAS)疼痛,次要观察指标为需要补救镇痛、重复股神经阻滞和住院时间。

结果

两组患者在术后 6 小时的 VAS 评分无统计学差异,但在 12、24 和 48 小时时,两组患者的 VAS 评分、需要补救镇痛、重复股神经阻滞和住院时间均有统计学差异,ACB+MPI+IAEC 组更有优势。

结论

罗哌卡因间断膝关节内浸润是一种安全、可重复、有效的方法,可控制 TKA 后 48 小时内的疼痛。

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