低剂量阿糖胞苷治疗骨髓增生异常综合征的当前结果。一项合作方案（38例患者）的初步结果及文献综述。
Present results of the treatment of myelodysplastic syndromes with low-dose cytosine arabinoside. Preliminary results of a cooperative protocol (38 patients) and review of the literature.
作者信息
Chomienne C, Najean Y, Degos L, Thomas G, Baumelou E, Calvo F, Casassus P, Ciccone F, Fenaux P, Gris J C
机构信息
Department of Nuclear Medicine, Institut National de la Santé, Hôpital Saint-Louis, Paris, France.
出版信息
Acta Haematol. 1987;78 Suppl 1:109-15. doi: 10.1159/000205914.
In vitro differentiating agents causing little bone marrow aplasia have been proposed as a specific therapy of myelodysplastic syndromes with excess of blasts. A critical review of the published data is presented. The preliminary results of a cooperative protocol using very low dosage of cytosine arabinoside (3mg/m2/twice daily) with or without androgens are given.
已提出将引起轻度骨髓再生障碍的体外分化剂作为伴有过多原始细胞的骨髓增生异常综合征的特异性治疗方法。本文对已发表的数据进行了批判性综述。给出了一项合作方案的初步结果，该方案使用极低剂量的阿糖胞苷（3mg/m²/每日两次），联合或不联合雄激素。
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