Mangoni L, Degliantoni G, Porcellini A, Carella A M, Alessandrino E P, Aglietta M, Resegotti L, Torlontano G, Coleselli P, Mozzana R
Cattedra di Ematologia, Parma, Italia.
Acta Haematol. 1987;78 Suppl 1:190-3. doi: 10.1159/000205929.
We evaluated the therapeutic efficacy of autologous bone marrow transplantation (ABMT) in 49 patients with acute leukemia, using ex-vivo-treated marrow with mafosfamide. This report summarizes data collected from 8 italian centers, involving 27 cases with acute lymphoid leukemia (ALL) and 22 cases with acute nonlymphoid leukemia (ANLL). The analysis of the results shows that the disease-free survival of ALL and ANLL are similar (45 and 52%, respectively) and no significant difference can be demonstrated between patients transplanted in CR1 or CR2, although there is a trend in favor of ABMT in CR1.
我们使用美法仑体外处理的骨髓，评估了自体骨髓移植（ABMT）对49例急性白血病患者的治疗效果。本报告总结了从8个意大利中心收集的数据，其中包括27例急性淋巴细胞白血病（ALL）患者和22例急性非淋巴细胞白血病（ANLL）患者。结果分析表明，ALL和ANLL的无病生存率相似（分别为45%和52%），在CR1期或CR2期接受移植的患者之间未显示出显著差异，尽管有在CR1期进行ABMT更具优势的趋势。
