Agha Ali M, Lopez-Mattei Juan, Donisan Teodora, Balanescu Dinu, Iliescu Cezar A, Banchs Jose, Kim Peter Y, Palaskas Nicolas L, Yusuf Syed, Gladish Greg, Hassan Saamir
Department of Cardiology, Division of Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Department of Diagnostic Radiology, Division of Diagnostic Imaging, he University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Open Heart. 2019 Jun 4;6(1):e001060. doi: 10.1136/openhrt-2019-001060. eCollection 2019.
Neuroendocrine neoplasms arise from the gastrointestinal tract and can lead to carcinoid syndrome. Carcinoid heart disease affects more than half of these patients and is the initial presentation of carcinoid syndrome in up to 20 % of patients. Carcinoid heart disease typically leads to valve dysfunction, but in rare instances, carcinoid tumours can also metastasise to the endocardium and myocardium. Cardiovascular imaging plays an integral role in the diagnosis and prognosis of carcinoid heart disease. The use of multimodality imaging techniques including echocardiography, cardiac MRI, cardiovascular CT and positron emission tomography have allowed for a more comprehensive assessment of carcinoid heart disease. In this review, we discuss the features of carcinoid heart disease observed on multimodality imaging, indications for obtaining imaging studies and their role in carcinoid heart disease management.
神经内分泌肿瘤起源于胃肠道,可导致类癌综合征。类癌性心脏病影响超过半数的此类患者,在高达20%的患者中是类癌综合征的首发表现。类癌性心脏病通常导致瓣膜功能障碍,但在罕见情况下,类癌肿瘤也可转移至心内膜和心肌。心血管成像在类癌性心脏病的诊断和预后中起着不可或缺的作用。使用包括超声心动图、心脏磁共振成像、心血管计算机断层扫描和正电子发射断层扫描在内的多模态成像技术,能够对类癌性心脏病进行更全面的评估。在本综述中,我们讨论了多模态成像观察到的类癌性心脏病的特征、进行成像检查的指征及其在类癌性心脏病管理中的作用。