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1
Safety and Efficacy of Bevacizumab Plus Standard-of-Care Treatment Beyond Disease Progression in Patients With Advanced Non-Small Cell Lung Cancer: The AvaALL Randomized Clinical Trial.贝伐珠单抗联合标准治疗在晚期非小细胞肺癌患者疾病进展后的安全性和疗效:AvaALL 随机临床试验。
JAMA Oncol. 2018 Dec 1;4(12):e183486. doi: 10.1001/jamaoncol.2018.3486. Epub 2018 Dec 13.
2
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC.阿替利珠单抗作为转移性非鳞状 NSCLC 一线治疗药物。
N Engl J Med. 2018 Jun 14;378(24):2288-2301. doi: 10.1056/NEJMoa1716948. Epub 2018 Jun 4.
3
LKB1 Expression Correlates with Increased Survival in Patients with Advanced Non-Small Cell Lung Cancer Treated with Chemotherapy and Bevacizumab.LKB1 表达与接受化疗和贝伐珠单抗治疗的晚期非小细胞肺癌患者的生存改善相关。
Clin Cancer Res. 2017 Jul 1;23(13):3316-3324. doi: 10.1158/1078-0432.CCR-16-2410. Epub 2017 Jan 24.
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The Potential of Combined Immunotherapy and Antiangiogenesis for the Synergistic Treatment of Advanced NSCLC.联合免疫治疗和抗血管生成治疗在晚期 NSCLC 协同治疗中的潜力。
J Thorac Oncol. 2017 Feb;12(2):194-207. doi: 10.1016/j.jtho.2016.10.003. Epub 2016 Oct 8.
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Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism.抗血管内皮生长因子癌症治疗的停药会通过肝脏再血管化机制促进转移。
Nat Commun. 2016 Sep 1;7:12680. doi: 10.1038/ncomms12680.
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International Experts Panel Meeting of the Italian Association of Thoracic Oncology on Antiangiogenetic Drugs for Non-Small Cell Lung Cancer: Realities and Hopes.意大利胸外科肿瘤学会抗血管生成药物治疗非小细胞肺癌国际专家小组会议:现实与希望。
J Thorac Oncol. 2016 Jul;11(7):1153-69. doi: 10.1016/j.jtho.2016.03.015. Epub 2016 Apr 5.
7
Maintenance therapy with pemetrexed and bevacizumab versus pemetrexed monotherapy after induction therapy with carboplatin, pemetrexed, and bevacizumab in patients with advanced non-squamous non small cell lung cancer.在晚期非鳞状非小细胞肺癌患者中,使用卡铂、培美曲塞和贝伐单抗进行诱导治疗后,培美曲塞和贝伐单抗维持治疗与培美曲塞单药维持治疗的比较。
Eur J Cancer. 2016 May;58:30-7. doi: 10.1016/j.ejca.2016.01.013. Epub 2016 Feb 27.
8
Bevacizumab beyond disease progression after first-line treatment with bevacizumab plus chemotherapy in advanced nonsquamous non-small cell lung cancer (West Japan Oncology Group 5910L): An open-label, randomized, phase 2 trial.贝伐单抗联合化疗一线治疗晚期非鳞状非小细胞肺癌后疾病进展时继续使用贝伐单抗(日本西部肿瘤学组5910L):一项开放标签、随机、2期试验
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Bevacizumab in Patients with Nonsquamous Non-Small Cell Lung Cancer and Asymptomatic, Untreated Brain Metastases (BRAIN): A Nonrandomized, Phase II Study.贝伐珠单抗治疗非鳞状非小细胞肺癌伴无症状、未经治疗的脑转移患者(BRAIN):一项非随机、二期研究。
Clin Cancer Res. 2015 Apr 15;21(8):1896-903. doi: 10.1158/1078-0432.CCR-14-2082. Epub 2015 Jan 22.
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Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study.厄洛替尼单药或联合贝伐珠单抗作为 EGFR 突变的晚期非鳞状非小细胞肺癌患者的一线治疗(JO25567):一项开放标签、随机、多中心、Ⅱ期研究。
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Editorial on "The AvaALL Randomized Clinical Trial".

作者信息

Bonanno Laura, Pavan Alberto, Pasello Giulia, Indraccolo Stefano

机构信息

Medical Oncology 2, Istituto Oncologico Veneto IOV - IRCCS, Padova, Italy.

Department of Surgery, Oncology and Gastroenterology, Università degli Studi di Padova, Padova, Italy.

出版信息

J Thorac Dis. 2019 May;11(Suppl 9):S1237-S1240. doi: 10.21037/jtd.2019.02.62.

DOI:10.21037/jtd.2019.02.62
PMID:31245096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6560574/
Abstract
摘要