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促性腺激素释放激素激动剂亮丙瑞林治疗后卵巢对人绝经期促性腺激素的反应。

Ovarian response to human menopausal gonadotropin after therapy with the gonadotropin-releasing hormone agonist leuprolide.

作者信息

Nader S, Berkowitz A S, Winkel C A

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas Health Science Center, Houston.

出版信息

Am J Obstet Gynecol. 1988 Feb;158(2):403-4. doi: 10.1016/0002-9378(88)90164-0.

DOI:10.1016/0002-9378(88)90164-0
PMID:3124624
Abstract

Two of three patients receiving leuprolide, a gonadotropin-releasing hormone agonist, demonstrated a decreased ovarian response to gonadotropin stimulation that was consistent with that of an earlier report involving two cases. It would appear that this agonist has direct antigonadal actions.

摘要

三名接受促性腺激素释放激素激动剂亮丙瑞林治疗的患者中有两名表现出卵巢对促性腺激素刺激的反应降低，这与之前一篇涉及两例病例的报告结果一致。看来这种激动剂具有直接的抗性腺作用。

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