南亚成年人多重用药的发病率、患病率、风险因素及健康后果：一项系统评价方案

Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol.

作者信息

Khan Nusrat, Chattopadhyay Kaushik, Leonardi-Bee Jo

机构信息

Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.

The Nottingham Centre for Evidence-Based Healthcare: a Joanna Briggs Institute Centre of Excellence.

出版信息

JBI Database System Rev Implement Rep. 2019 Nov;17(11):2370-2377. doi: 10.11124/JBISRIR-D-18-00001.

DOI:10.11124/JBISRIR-D-18-00001

PMID:31246733

Abstract

OBJECTIVE

The objective of the systematic review is to summarize the incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia.

INTRODUCTION

Several studies have been conducted in South Asia on the incidence, prevalence, risk factors and health consequences of polypharmacy in adults. Until now, no systematic review has been conducted on this topic.

INCLUSION CRITERIA

Related epidemiological studies conducted on adults (aged 18 years and over) and residing in any country within South Asia (i.e. Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan and Sri Lanka) will be eligible for inclusion.

METHODS

MEDLINE, Embase, CINAHL, PsycINFO, BNI, Web of Science, Scopus and AMED databases will be searched to identify published studies. The search for unpublished studies will be undertaken in EThOS, OpenGrey and ProQuest Dissertations and Theses. Databases will be searched from their inception dates and no language restrictions will be applied. The JBI systematic review methodology will be followed to conduct the review. Data synthesis will be conducted using narrative synthesis and meta-analyses, where appropriate.

摘要

目的

本系统评价的目的是总结南亚成年人多重用药的发病率、患病率、危险因素及健康后果。

引言

南亚已开展了多项关于成年人多重用药的发病率、患病率、危险因素及健康后果的研究。到目前为止，尚未对该主题进行系统评价。

纳入标准

对居住在南亚任何国家（即阿富汗、孟加拉国、不丹、印度、马尔代夫、尼泊尔、巴基斯坦和斯里兰卡）的成年人（18岁及以上）进行的相关流行病学研究将符合纳入条件。

方法

将检索MEDLINE、Embase、CINAHL、PsycINFO、BNI、科学网、Scopus和AMED数据库以识别已发表的研究。将在EThOS、OpenGrey和ProQuest学位论文数据库中搜索未发表的研究。将从数据库的起始日期开始进行搜索，且不设语言限制。将遵循JBI系统评价方法进行评价。将酌情使用叙述性综合分析和荟萃分析进行数据综合。