Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Keck Medical Center at the University of Southern California, Los Angeles, Calif.
Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Keck Medical Center at the University of Southern California, Los Angeles, Calif.
J Vasc Surg. 2019 Dec;70(6):1776-1781. doi: 10.1016/j.jvs.2019.04.461. Epub 2019 Jun 24.
Treatment of type B aortic dissections with thoracic endovascular aortic repair (TEVAR) has been adopted in many centers with the goal of covering the proximal entry tear. Coverage of the left subclavian artery (LSCA) is commonly required to achieve a dissection-free proximal seal zone. A novel thoracic single side-branched (TSSB) endograft device offers a potential off-the-shelf option to achieve total endovascular incorporation of LSCA during zone 2 TEVAR. The aim of this study was to determine what percentage of patients with type B aortic dissection who require zone 2 TEVAR meet the anatomical requirements for this device.
All consecutive patients undergoing TEVAR for type B aortic dissections at a single institution from 2006 to 2016 were evaluated. Three-dimensional centerline reconstruction of preoperative computed tomography angiography was performed to identify the diameter of the aorta, distances between branch vessels, diameter of the target branch vessel, and location of the primary entry tear. Only patients who met criteria for zone 2 TEVAR were included in the analysis. The primary outcome was percentage of patients that meet all anatomical requirements for TSSB. Individual criteria were evaluated independently, and results were stratified by dissection chronicity.
Eighty-seven patients who underwent TEVAR for Stanford type B aortic dissections were reviewed. Fifty-seven (66%) would have required zone 2 TEVAR. Indications for TEVAR were malperfusion (12), aneurysm (15), persistent pain (22), rupture (3), uncontrolled hypertension (5), and other (3). Mean follow-up was 19 months (range, 1-72 months). Only 16 of the 57 patients (28%) met all the requirements for anatomic suitability. The primary contributor was that only 49% of patients had sufficient length between arch branches to prevent coverage of a proximal branch.
Although the new TSSB device can allow for a more proximal seal zone and eliminate the need for open aortic arch debranching, only 28% of patients with type B dissection who required zone 2 TEVAR met all the anatomic requirements for this device. Future devices will need to account for the short distance between the left carotid and LSCA to be more broadly applicable.
许多中心采用胸主动脉腔内修复术(TEVAR)治疗 B 型主动脉夹层,目的是覆盖近端入口撕裂。为了实现无夹层的近端密封区,通常需要覆盖左锁骨下动脉(LSCA)。一种新型的胸单侧分支(TSSB)血管内移植物装置为在 2 区 TEVAR 期间完全血管内纳入 LSCA 提供了一种潜在的现成选择。本研究的目的是确定需要 2 区 TEVAR 的 B 型主动脉夹层患者中,有多少患者符合该装置的解剖要求。
对 2006 年至 2016 年在一家机构接受 TEVAR 治疗的所有连续 B 型主动脉夹层患者进行评估。对术前 CT 血管造影的三维中心线重建,以确定主动脉直径、分支血管之间的距离、目标分支血管直径和主要入口撕裂的位置。仅分析符合 2 区 TEVAR 标准的患者。主要结果是符合 TSSB 所有解剖要求的患者百分比。独立评估个别标准,并按夹层慢性期分层结果。
回顾了 87 例接受 TEVAR 治疗的 Stanford B 型主动脉夹层患者。57 例(66%)需要 2 区 TEVAR。TEVAR 的指征为灌注不良(12 例)、动脉瘤(15 例)、持续性疼痛(22 例)、破裂(3 例)、未控制的高血压(5 例)和其他(3 例)。平均随访 19 个月(1-72 个月)。仅有 57 例患者中的 16 例(28%)符合所有解剖学适合性的要求。主要原因是只有 49%的患者弓支之间有足够的长度,以防止近端支的覆盖。
尽管新型 TSSB 装置可允许更靠近近端的密封区,并消除开放主动脉弓分支的需要,但仅 28%需要 2 区 TEVAR 的 B 型夹层患者符合该装置的所有解剖学要求。未来的装置需要考虑到左颈总动脉和 LSCA 之间的短距离,以更广泛地适用。