Centre for Disease Modelling, Department of Mathematics and Statistics, York University, Toronto, M3J 1P3, Canada.
Manifold Data Mining, Toronto, M3B 3J5, Canada.
Sleep Med. 2019 Sep;61:26-30. doi: 10.1016/j.sleep.2019.04.015. Epub 2019 May 9.
This study aimed to explore the association between sleep problems and health-related quality of life (HRQoL) in Canadian adults with chronic diseases, and whether mental illness can mediate the association.
Data were drawn from the Canadian Community Health Survey, 2015. A total of 10,900 participants aged ≥18 years and diagnosed with chronic diseases were enrolled in this study.
Of these participants, 23.6% (95% CI 22.1, 25.2) suffered from severe impairment of HRQoL. Extreme sleep durations, including both short (<5, 5 to <6, and 6 to <7 h) and long (9 to <10, and ≥10 h) sleep durations, were significantly associated with severe impairment of HRQoL (compared to 7 to <8 h). Insomnia was also independently associated with severe impairment of HRQoL when compared to those without insomnia. In the mediation analyses, mental illness was shown to partly mediate the associations of extreme sleep durations and insomnia with severe impairment of HRQoL.
In conclusion, both extreme sleep durations and insomnia were independently associated with severe impairment of HRQoL in adults with chronic diseases, and mental illness partly mediated the association.
本研究旨在探讨加拿大慢性病成年人睡眠问题与健康相关生活质量(HRQoL)之间的关系,以及精神疾病是否可以调节这种关系。
数据来自 2015 年加拿大社区健康调查。共有 10900 名年龄≥18 岁且被诊断患有慢性病的参与者纳入本研究。
这些参与者中,23.6%(95%CI 22.1, 25.2)存在严重的 HRQoL 受损。极端睡眠时间,包括短(<5、5 至<6 和 6 至<7 小时)和长(9 至<10 和≥10 小时)睡眠时间,与严重的 HRQoL 受损显著相关(与 7 至<8 小时相比)。与无失眠者相比,失眠也与严重的 HRQoL 受损独立相关。在中介分析中,精神疾病部分介导了极端睡眠时间和失眠与严重 HRQoL 受损之间的关联。
总之,极端睡眠时间和失眠与慢性病成年人的严重 HRQoL 受损独立相关,精神疾病部分介导了这种关联。