Institute of Neurogenetics, University of Lübeck, Lübeck, Germany; Department of Neurology, University Hospital Schleswig-Holstein, Campus Lübeck, Germany.
Institute of Neurogenetics, University of Lübeck, Lübeck, Germany.
Parkinsonism Relat Disord. 2019 Aug;65:284-285. doi: 10.1016/j.parkreldis.2019.06.020. Epub 2019 Jun 23.
The diagnosis of Parkinson's disease (PD) in patients carrying mutations in the Parkin gene is frequently delayed. We confirmed this finding in a sample of nine biallelic Parkin-PD patients with a mean delay of nine years and found an inverse relationship between diagnostic delay and age at onset.
携带 Parkin 基因突变的帕金森病 (PD) 患者的诊断经常被延误。我们在一个平均诊断延迟 9 年的 9 例 Parkin-PD 双等位基因突变患者样本中证实了这一发现，并发现诊断延迟与发病年龄呈反比关系。
